T‐Wave Variability as a Risk Stratifier in Patients with Dilated Cardiomyopathy

Abstract

Max TVAR was a predictor of arrhythmic events in patients with dilated cardiomyopathy at rest.

T-Wave Amplitude Variability and the Risk of Death in Chagas Disease

“…[3][4][5][6][7][8][9] Measurement of beat-to-beat T-wave amplitude variability (TWV) has been described as a promising new technique for the stratification of arrhythmic risk in postmyocardial infarction patients with depressed ventricular function 10 or dilated cardiomyopathy. 11 More recently, an increase in TWV has been reported in the long-QT syndrome 12 and in competitive athletes. 13 As repolarization abnormalities are common in ChD and both T-wave axis deviation 9 and increased QT interval dispersion or duration 8 were identified as independent predictors of mortality in chronic ChD patients, in the present study we evaluated the prognostic value of TWV in ChD patients in addition to traditional prognostic predictors.…”

“…Measurement of beat‐to‐beat T‐wave amplitude variability (TWV) has been described as a promising new technique for the stratification of arrhythmic risk in postmyocardial infarction patients with depressed ventricular function 10 or dilated cardiomyopathy 11 . More recently, an increase in TWV has been reported in the long‐QT syndrome 12 and in competitive athletes 13 .…”

Cardiac repolarization instability during psychological stress in patients with ventricular arrhythmias

“…Beat-to-beat variability of the T-wave amplitudes at rest has been used for arrhythmia risk stratification in patients with LQTS 16 , dilated cardiomyopathy 17 , ischemic cardiomyopathy 18 , and Chagas disease. 19 Coudrec et al have shown the variability of T-wave amplitudes >59 μV was predictive of future arrhythmic events in patients with ICDs.…”

T-Wave Variability for the Prediction of Fast Ventricular Arrhythmias

“…In the present model, the best cut-off was ∆T-var cardiomyopathy. 15 Previous studies noted a lower maximum TAV in patients who survived a cardiac arrest and a decrease of TAV in patients with LV reverse remodeling after CRT implantation. 14, 15 To date, only 1 study reported on ICD patients with increased T-wave alternans and TAV shortly before the onset of spontaneous VA. 16 In contrast, Levitt et al found no differences in TAV between high-risk patients and healthy controls, although TAV was reproducible in patients with ventricular dysfunction.…”

“…15 Previous studies noted a lower maximum TAV in patients who survived a cardiac arrest and a decrease of TAV in patients with LV reverse remodeling after CRT implantation. 14, 15 To date, only 1 study reported on ICD patients with increased T-wave alternans and TAV shortly before the onset of spontaneous VA. 16 In contrast, Levitt et al found no differences in TAV between high-risk patients and healthy controls, although TAV was reproducible in patients with ventricular dysfunction. 17 These conflicting results suggest that T-var calculation based solely on TAV may not be a reliable tool for VA prediction in patients with electrical conduction problems or ventricular dysfunction.…”