“…CD4 + Th cells, including Th1, Th2, and Th17 cells, have protective and pathological functions that are dependent on their cytokines. For instance, Th1 cells show antifibrotic and antineoplastic properties by producing interferon (IFN)‐γ, whereas Th2 cells are associated with allergic reactions and promotion of fibrosis and tumourigenesis by secreting IL‐4, IL‐5, and IL‐13 7,8 . Th17 cells are implicated in multiple immune reactions, 4,9 including infectious inflammation, autoimmune diseases, 10 tissue repair, 8,11 and cancer, 12,13 through production of the effector cytokines IL‐17A‐F (six family members), IL‐22, and IL‐21.…”