T-cell lymphoma of the upper eyelid: A case report and review of the literature

Verret, D. J.; DeFatta, Robert J.; Ducic, Yadranko

doi:10.1016/j.suronc.2006.11.001

Cited by 5 publications

(2 citation statements)

References 15 publications

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“…For advanced cases of MF, chemotherapeutic agents such as doxorubicin, gemcitabine, and chlorambucil may be considered [6]. There are few cases of surgical management of MF in the current literature, and currently, there are no recommendations regarding margins for excision to reduce local recurrence [11]. This case demonstrates that surgical management should be considered as an adjunctive treatment option to relieve symptoms secondary to refractory MF.…”

Section: Discussionmentioning

confidence: 99%

The Role of Surgery to Relieve Symptomatic Cutaneous T-Cell Lymphoma Refractory to Medical Treatments

Zhang,

Hecox,

Dogar

et al. 2024

Case Reports in Oncological Medicine

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Background: Though mycosis fungoides (MF) is the most common type of cutaneous T-cell lymphoma (CTCL), it has no curative treatment. The aim of current topical and systemic treatment is centered around relieving symptoms and optimizing disease-free time. The use of surgical management to achieve the same goals of symptomatic reduction is not well described in the current literature.Methods: We present a case of refractory MF that failed chemotherapy, radiotherapy, and UV light therapy. Despite medical management, the tumor burden progressed to significant compression neuropathy of the ulnar and median nerves.Results: To reduce tumor burden and attempt to provide symptomatic relief, a surgical plan was developed to include radical resection of the tumor of the left upper extremity (LUE) with release of the cubital tunnel, carpal tunnel, Guyon canal, and coverage with split-thickness skin graft. The patient reported decreased symptomatology interfering with her daily activities and, overall, a better quality of life postoperatively.Conclusion: Surgical intervention, in addition to established medical standards of care, for symptomatic relief of compression neuropathy from tumor mass effect for refractory CTCL should be considered to achieve quality of life goals for patients.

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Section: Discussionmentioning

confidence: 99%

The Role of Surgery to Relieve Symptomatic Cutaneous T-Cell Lymphoma Refractory to Medical Treatments

Zhang,

Hecox,

Dogar

et al. 2024

Case Reports in Oncological Medicine

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“…4 A case report of ocular CTCL described simple surgical resection without specific margins and reported a 3.5-year recurrence-free follow-up. 8 Other rare subtypes of ocular cutaneous lymphoma have been treated effectively with surgery alone. 3 We elected to use a 1-cm margin for surgical resection to maximally reduce locoregional recurrence in the setting of our complex thumb reconstruction.…”

Section: Discussionmentioning

confidence: 99%

Surgical Excision of Mycosis Fungoides Using Thumb-Sparing Reconstruction

McEvenue

Kim

Binhammer

2016

Hand (New York, N,Y.)

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Background: The differential for soft tissue tumors of the hand and upper limb is broad. Hematologic malignancy remains quite low on the differential for soft tissue tumors involving the hand, and there is little in the literature describing surgical management of such cutaneous manifestations. When the tumor is large or involves the thumb, careful consideration of reconstructive options is required. Methods: We present a rare case of an aggressively enlarging mycosis fungoides, a cutaneous T-cell lymphoma tumor, involving the thumb. This tumor had a history of multiple failed treatment attempts, including radiation and chemotherapy. Results: Our surgical plan was a reverse radial forearm osteocutaneous flap. Conclusion: A reverse radial osteocutaneous forearm flap was successfully used to avoid thumb amputation and preserve thumb function.

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