T cell interactions with microglia in immune-inflammatory processes of ischemic stroke
Yuxiao Zheng,
Zilin Ren,
Ying Liu
et al.
Abstract:The primary mechanism of secondary injury after cerebral ischemia may be the brain inflammation that emerges after an ischemic stroke, which promotes neuronal death and inhibits nerve tissue regeneration. As the first immune cells to be activated after an ischemic stroke, microglia play an important immunomodulatory role in the progression of the condition. After an ischemic stroke, peripheral blood immune cells (mainly T cells) are recruited to the central nervous system by chemokines secreted by immune cells… Show more
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