T-1 Cells are HeLa and Not of Normal Human Kidney Origin

Abstract

of results from strictly local mappings between neighboring points in successive frames.As a control experiment to verify that this superior discriminability of the coherent spherical pattern was associated with its three-dimensionality, we also examined performance under an analogous set of conditions with two unconnected but superimposed rectilinear plane patterns. The pattern of results for these planar patterns was very different, with no superiority in the detectability of the perfectly correlated pattern, no effect from small reductions in the correlation, and a competitive interference rather than global organization between two planes displaced in opposite directions.Thus, a single discrete projective transformation provides sufficient information for the detection of structure and motion in three dimensions. The underlying visual process is self-organizing, yielding a nonlinear stability sensitive to the global coherence of the changing optical pattern.

Amplification of sodium- and potassium-activated adenosinetriphosphatase in HeLa cells by ouabain step selection.

“…The identity of this phosphopeptide is not known, nor is the reason for its altered expression in C ÷ and C-cells understood. Table I summarizes the results of previous chromosomes studies performed in known and suspected HeLa cell lines (32)(33)(34). The karyotype of our HeLa cell line is consistent with the designation of HeLa $3 with a few modifications.…”

Device fracture and severe tricuspid regurgitation after percutaneous closure of perimembranous ventricular septal defect: A case report

“…A lack of vigilance in cell acquisition and identity testing has plagued scientific studies and publications since the inception of cell line methods 42–47. In the 1970s and 1980s, examples of interspecies and intraspecies cross‐contamination of human cell lines was documented by Nelson‐Rees 43, 45.…”

Cell cross-contamination in cell cultures: The silent and neglected danger

“…Later on, Nelson-Rees and his collaborators summarized experience from 466 laboratories and found that 16% of the cell lines were incorrectly identified (Nelson-Rees, 1978;Hay et al, 1992). T-1 cell line cells used by many authors in radiation biology, which were supposed to be diploid normal kidney cells, were in fact HeLa-adenocarcinoma-derived heteroploid cells from uterine cervix (Nelson-Rees et al, 1980). Stulberg and colleagues investigated 246 cell lines specifically for evidence of CCC or mislabeling.…”