t(1;3)(p36;q21)

A Novel Case of Extreme Thrombocytosis in Acute Myeloid Leukemia Associated With Isochromosome 17q and Copy Neutral Loss of Heterozygosity

“…Extreme thrombocytosis is rare in AML, and only a few cases have been described with chromosome 3 abnormalities [ 4 , 5 ]. In addition, the loss of heterozygosity (LOH) affecting chromosome 7q is common in AML and MDS, suggesting the essential role of this region in disease phenotypes and in clonal evolution.…”