Systemic sclerosis and tachycardia–bradycardia syndrome: a case report

Abstract

Background Systemic sclerosis is a multisystemic character autoimmune disease. It is characterized by vascular dysfunction and progressive fibrosis affecting mainly the skin but also different internal organs. All heart structures are commonly affected, including the pericardium, myocardium, and conduction system. However, tachycardia–bradycardia syndrome is not common in the literature as a cardiac complication of systemic sclerosis. Case presentation We report a case of tachycardia–bradycardia syndrome in a 46-year-old Moroccan woman followed for systemic sclerosis with cutaneous, vascular, and articular manifestations. The diagnosis was based mainly on patient-reported symptoms and electrocardiogram data. A permanent pacemaker was implanted, allowing the introduction of beta-blockers with good outcomes. Conclusions This case aims to show that even minor electrocardiogram abnormalities should be monitored in this group of patients, preferably by 24-hour ambulatory electrocardiogram because they could be a good indicator of the activity and progression of cardiac fibrosis.

A case report of clubbing as the initial sign of systemic sclerosis sine scleroderma: A rare possible presentation

“…3 Despite being a less common variant, ssSSc often presents challenges in diagnosis due to its varied clinical manifestations and potential underdiagnosis. 4,5 Delays in the diagnosis of ssSSc can have detrimental consequences, as the disease frequently involves vital internal organs such as the cardiovascular and respiratory systems. Studies have indicated variable 10-year survival rates ranging from 50% to 84% in SSc, highlighting the importance of early identification and intervention.…”

“…The epidemiology of ssSSc remains poorly understood, with estimates suggesting that it accounts for approximately 5% of all SSc cases 3 . Despite being a less common variant, ssSSc often presents challenges in diagnosis due to its varied clinical manifestations and potential underdiagnosis 4,5 …”