Systemic Lupus Erythematosus Complicated With Hypoplastic Marrow and Haemophagocytosis: A Case Report

Abstract

Association of systemic lupus erythromatosus with hemophagocytic lymphohistiocytosis (HLH) has been reported by many authors 1,2,3,4 however association of systemic lupus erythromatosus with hemophagocytic lymphohistiocytosis and hypoplastic bone marrow is quite rare. Here we are reporting a case of HLH developing in a known case of SLE presenting with hypoplastic bone marrow in a 45 years old female, on low dose steroid therapy who presented with febrile pancytopenia, hepatosplenomegaly, hyperferritinemia with evidence of bone marrow hypoplasia and haemophagocytosis.