2023
DOI: 10.1093/intimm/dxad021
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Systemic immunometabolism and responses to vaccines: insights from T and B cell perspectives

Abstract: Vaccination stands as the cornerstone in the battle against infectious diseases, and its efficacy hinges upon multifaceted host-related factors encompassing genetics, age, and metabolic status. Remarkably, suboptimal immune responses triggered by metabolic dysregulation is frequently observed in susceptible populations – ranging from malnourished individuals to the obese and elderly – pose a formidable threat to vaccine efficacy. The emerging field of immunometabolism aims to unravel the intricate interplay be… Show more

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Cited by 3 publications
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