Systemic Diseases in Dakar (Senegal): Spectrum, Epidemiological Aspect and Diagnostic Time-Limit

Kane, Baïdy Sy; Niasse, Moustapha; Ndiaye, Abdoul Aziz; Ndao, Awa Cheikh; Djiba, Boundia; Diack, Ngoné Diaba; Fall, Babacar; Ndour, Michel Assane; Dieng, Mohamed; Dia, D.; Diagne, N.; Faye, Atoumane; Leye, Abdoulaye; Gning, S. B.; Ndongo, S.; Pouye, Abdoulaye

doi:10.4236/ojim.2018.83019

Cited by 12 publications

(11 citation statements)

References 23 publications

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“…In this series, the mean age was 44 + 12 years with extremes from 24 to 64 years. This mean age was comparable to that found by Kane et al [7] in Dakar (43.76 years). A clear female predominance with a male to female sex ratio of 0.09 was found.…”

Section: Discussionsupporting

confidence: 90%

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Cardiac Diseases During Systemic Inflammatory Diseases in the Internal Medicine and Medical Oncology Department of NTHC-HKM of Cotonou

Angèle¹,

Armand²,

Anthelme³

et al. 2021

AJIM

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Systemic inflammatory diseases are characterized by multivisceral involvement at some point in their evolution.This involvement can concern almost all organs, including the heart. Each systemic condition has a unique cardiac expression. The target of this study is to determine the frequency of cardiac involvement in systemic inflammatory diseases. This study is a cross-sectional, descriptive, and analytical study that was conducted within 07 months. The aim was to screen 23 patients followed for systemic inflammatory diseases for cardiac involvement. The mean age was 44 (±12) years old with a minimum of 24 and a maximum 64 years. Most of patients were women with a sex ratio (M/F) of 0.09. An echocardiographic abnormality was found in 26.1% of patients and 73.1% had an ECG abnormality. They included left atrial hypertrophy (43.4%), left ventricular hypertrophy (30.4%), right axial deviation (26.1%), low voltage (21.7%), right atrial hypertrophy (8.6%), S1Q3 appearance (8, 6%), pulmonary hypertension (8.6%), repolarization disorders (8.6%), sinus tachycardia (8.6%), middle tricuspid insufficiency (4.3%), middle pulmonary insufficiency (4.3%), and pericarditis (4.3%). Patients with systemic inflammatory diseases had cardiac disorders with rare clinical manifestations but with an incidental discovery either on ECG or on cardiac echodoppler. Hence, a systematic cardiac exploration in these patients was essential.

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Section: Discussionsupporting

confidence: 90%

“…A clear female predominance with a male to female sex ratio of 0.09 was found. This female predominance was also found by several other authors [5][6][7][8][9].…”

Section: Discussionsupporting

confidence: 88%

Cardiac Diseases During Systemic Inflammatory Diseases in the Internal Medicine and Medical Oncology Department of NTHC-HKM of Cotonou

Angèle¹,

Armand²,

Anthelme³

et al. 2021

AJIM

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“…It has been rarely reported in sub-Saharan Africa [8]. On a large multicenter study about systemic diseases in Senegal, we described only three cases of ASS in 10 years [11].…”

Section: Discussionmentioning

confidence: 78%

“…IIM, and ASS are rarely reported among black Africans [7] [8] [9] [10] [11]. We discuss 03 Senegalese cases of ASS and we hope that these observations will add to medical literature and aid in early diagnosis of other patients presenting with similar features.…”

Section: Introductionmentioning

confidence: 94%

Antisynthetase Syndrome in Senegalese Patients: Report of Three Cases

Kane¹,

Niasse²,

Ndour³

et al. 2019

OJIM

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Introduction: Antisynthetase syndrome is an original entity and rare autoimmune myositis and systemic disease, characterized clinically by a wide spectrum of clinical manifestations and the presence of autoantibodies directed against aminoacyl RNAt synthetases. We describe this disease in 03 Senegalese patients. Observations: The first patient was a 49-years-old black woman who was referred in our department after 06-months of follow-up for a misdiagnosis of tuberculosis. The clinical examination revealed polyarthritis, muscle weakness, chronic cough with crackling rales at the pulmonary bases, Raynaud phenomenon and dry syndrome. The second patient, a 21-years-old black woman, had polyarthritis and a progressive muscle weakness. The clinical examination showed also cutaneous signs including an erythema on the dorsal part of the fingers and the presence of the heliotrope erythema on the eyes. The last patient was a 52 years-old black woman. His clinical examination showed polyarthritis, muscle weakness and an appearance of mechanics' hands. The creatinine phosphokinase was at 6.26 × N, 40.3 × N and 33.64 × N respectively in our patients. The chest computer tomography revealed an interstitial lung disease with a pattern of non-specific interstitial pneumonia in all three patients. The autoantibodies anti-Jo1 was also positive in all patients.

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“…As in our series, some authors such as Konaté et al [21] and Sougué et al [20] in Burkina Faso reported 01 case of systemic sarcoidosis in their study. In Senegal, Kane et al, reported 03 cases of Still's disease in their series on systemic diseases [24].…”

Section: Discussionmentioning

confidence: 99%

Panorama of Autoimmune and Autoinflammatory Diseases in Internal Medicine at the University Hospital Center (UHC) of the Point G

Kaya¹,

Kaly²,

Sy³

et al. 2021

OJIM

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Introduction: Panorama studies of autoimmune and auto-inflammatory diseases are still very little carried out in Africa and particularly in Mali. The objective of this descriptive study with retrospective collection was to describe the epidemiological and clinical profile of all autoimmune and auto-inflammatory diseases in the department of internal medicine at the University Hospital Center of the Point G. Methods: This was a descriptive study with a retrospective survey of the records of patients hospitalized for autoimmune and auto-inflammatory diseases in the department of internal medicine at the CHU of Point G for a study period of 15 years from January 1, 2005 to December 31, 2019. We included in the study all patients hospitalized for autoimmune and auto-inflammatory diseases. Results: During the study period (January 31, 2005 to December 31, 2019), 6383 patients were hospitalized in internal medicine at the University Hospital Center of the Point G, of which 317 patients presented with autoimmune and/or auto-inflammatory disease with an average annual hospital recruitment rate of 21 ± 7.87 cases per year. The female sex accounted for 64.

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Systemic Diseases in Dakar (Senegal): Spectrum, Epidemiological Aspect and Diagnostic Time-Limit

Cited by 12 publications

References 23 publications

Cardiac Diseases During Systemic Inflammatory Diseases in the Internal Medicine and Medical Oncology Department of NTHC-HKM of Cotonou

Cardiac Diseases During Systemic Inflammatory Diseases in the Internal Medicine and Medical Oncology Department of NTHC-HKM of Cotonou

Antisynthetase Syndrome in Senegalese Patients: Report of Three Cases

Panorama of Autoimmune and Autoinflammatory Diseases in Internal Medicine at the University Hospital Center (UHC) of the Point G

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