Systemic and mucosal adaptive immunity to SARS-CoV-2 during the Omicron wave in patients with chronic lymphocytic leukemia

Abstract

Not available.

SARS-CoV-2 breakthrough infections enhance T cell response magnitude, breadth, and epitope repertoire

“…Previous studies including our own have addressed the ability of T cells to still be able to recognize mutated epitopes of a specific SARS-CoV-2 variant, particularly in the context of Omicron and Omicron sub-lineages. 13 , 14 , 19 , 76 , 77 , 78 , 79 , 80 We have additionally speculated that infection with SARS-CoV-2 variants should be able to also generate de novo responses, 81 although experimental data were lacking in support of this hypothesis. Our data show that infection with one variant does not compromise the capacity of T cell responses to broadly recognize other variants.…”