Systemic and local vascular inflammation and arterial reactive oxygen species generation in patients with advanced cardiovascular diseases
Joanna Sulicka-Grodzicka,
Piotr Szczepaniak,
Ewelina Jozefczuk
et al.
Abstract:BackgroundSystemic inflammation may cause endothelial activation, mediate local inflammation, and accelerate progression of atherosclerosis. We examined whether the levels of circulating inflammatory cytokines reflect local vascular inflammation and oxidative stress in two types of human arteries.MethodsHuman internal mammary artery (IMA) was obtained in 69 patients undergoing coronary artery bypass graft (CABG) surgery and left anterior descending (LAD) artery was obtained in 17 patients undergoing heart tran… Show more
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