Systemic Administration of Cowpea Mosaic Virus Demonstrates Broad Protection Against Metastatic Cancers
Young Hun Chung,
Zhongchao Zhao,
Eunkyeong Jung
et al.
Abstract:The key challenge in cancer treatment is prevention of metastatic disease which is therapeutically resistant and carries poor prognoses necessitating efficacious prophylactic approaches that prevent metastasis and recurrence. It is previously demonstrated that cowpea mosaic virus (CPMV) induces durable antitumor responses when used in situ, i.e., intratumoral injection. As a new direction, it is showed that CPMV demonstrates widespread effectiveness as an immunoprophylactic agent – potent efficacy is demonstra… Show more
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