Systematics and health effects of chemically distinct tannins in medicinal plants

Galloyl Glucoses from the Seeds of Cornus officinalis with Inhibitory Activity against Protein Glycation, Aldose Reductase, and Cataractogenesis ex Vivo

“…[30][31][32] However, tannins such as galloyl glucoses are not widely known as inhibitors of AR or protein glycation although their fundamental activities, e.g., reduction and antiperoxidation properties and marked biological and pharmacological activities of various potencies have been reported. 33 35) This is in good agreement with our present study (IC 50 ϭ0.70 mM for RLAR). To the best of our knowledge, this is the first report of compounds 1, 2, 4, 6, and 8 as inhibitors of AR and compounds 1-8 as inhibitor of AGE formation.…”

Wound Healing Activity of Various Extracts of Fruit of Pyrus Communis L. In Normal Rats

“…The above statement was proved by results of hydroxyproline estimation. Earlier studies revealed Flavonoids have therapeutic uses due to their anti-inflammatory, antifungal, antioxidant and wound healing properties [19][20][21][22] . Moreover, flavonoids and their derivatives are known to decrease lipid peroxidation by improving vascularity and preventing or slowing down the progress of cell necrosis.…”

Generation of Mouse Monoclonal Antibody against (-)-Epigallocatechin Gallate

“…Since green tea catechin was first found to be a cancer preventive, the results with EGCG and green tea catechins have been reported by numerous scientists, [1][2][3][4][5][6][7][8][9][10] but understanding of the molecular mechanism has somehow not deepened. [11][12][13] The TG38 monoclonal antibody can be further utilized for basic and clinical experiments in cancer prevention, e.g., the monoclonal antibody makes it possible to investigate the metabolism of EGCG in serum and the distribution of EGCG in tissues and cells.…”

“…[1][2][3][4][5][6][7][8][9] The active principles are assumed to be green tea catechins, especially (Ϫ)-epigallocatechin gallate (EGCG), (Ϫ)-epicatechin gallate (ECG), (Ϫ)-epigallocatechin (EGC), and (Ϫ)-epicatechin (EC). 1,2) Green tea catechins have cancer preventive activities in vitro, in cell culture, and in vivo.…”

“…1,2) Green tea catechins have cancer preventive activities in vitro, in cell culture, and in vivo. [1][2][3][4][5][6][7][8][9] Specifically, they have a wide-range of target organs, such as digestive tract including esophagus, stomach, duodenum and colon, plus lung, liver, pancreas, breast, bladder, prostate, and skin. 1,2) Our exciting evidence showed that the consumption of 10 Japanese-size cups of green tea, supplemented with green tea extract, significantly prevented the recurrence of polyp development after colorectal polypectomy in humans (Moriwaki et al, personal communication).…”