Systematical identification of key genes and regulatory genetic variants associated with prognosis of esophageal squamous cell carcinoma
Linglong Gu,
Xinying Yue,
Siyuan Niu
et al.
Abstract:Esophageal squamous cell carcinoma (ESCC) stands as a highly lethal malignancy characterized by pronounced recurrence and metastasis, resulting in a bleak 5‐year survival rate. Despite extensive investigations, encompassing genome‐wide association studies, the identification of robust prognostic markers has remained elusive. In this study, leveraging four independent data sets comprising 404 ESCC patients, we conducted a systematic analysis to unveil pivotal genes influencing overall survival. our meta‐analysi… Show more
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