Systematic reviews reveal unrepresentative evidence for the development of drug formularies for poor and nonwhite populations

Odierna, Donna H.; Bero, Lisa

doi:10.1016/j.jclinepi.2009.01.009

Cited by 10 publications

(2 citation statements)

References 67 publications

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“…In addition, systematic reviews are often limited to randomized controlled trials (RCT). This could lead to systematic reviews that are not relevant or representative of the target population for the guidelines ( 9 ) .…”

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confidence: 99%

Study sponsorship and the nutrition research agenda: analysis of randomized controlled trials included in systematic reviews of nutrition interventions to address obesity

Fabbri

Chartres

Scrinis

et al. 2016

Public Health Nutr.

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mentioning

confidence: 99%

Study sponsorship and the nutrition research agenda: analysis of randomized controlled trials included in systematic reviews of nutrition interventions to address obesity

Fabbri

Chartres

Scrinis

et al. 2016

Public Health Nutr.

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“…Absent and/or poor quality evidence about health equity is identified by policy makers as a key limitation of research [ 8 , 9 ]. For example, evidence about poor or black or Hispanic populations is missing in reviews used for drug formulary development in the USA [ 10 ]. To address key public health objectives, decision-makers require the best evidence to guide appropriate consideration of the likely effects on health equity in their populations [ 3 , 11 , 12 ].…”

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confidence: 99%

Protocol for the development of a CONSORT-equity guideline to improve reporting of health equity in randomized trials

et al. 2015

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BackgroundHealth equity concerns the absence of avoidable and unfair differences in health. Randomized controlled trials (RCTs) can provide evidence about the impact of an intervention on health equity for specific disadvantaged populations or in general populations; this is important for equity-focused decision-making. Previous work has identified a lack of adequate reporting guidelines for assessing health equity in RCTs. The objective of this study is to develop guidelines to improve the reporting of health equity considerations in RCTs, as an extension of the Consolidated Standards of Reporting Trials (CONSORT).Methods/designA six-phase study using integrated knowledge translation governed by a study executive and advisory board will assemble empirical evidence to inform the CONSORT-equity extension. To create the guideline, the following steps are proposed: (1) develop a conceptual framework for identifying “equity-relevant trials,” (2) assess empirical evidence regarding reporting of equity-relevant trials, (3) consult with global methods and content experts on how to improve reporting of health equity in RCTs, (4) collect broad feedback and prioritize items needed to improve reporting of health equity in RCTs, (5) establish consensus on the CONSORT-equity extension: the guideline for equity-relevant trials, and (6) broadly disseminate and implement the CONSORT-equity extension.DiscussionThis work will be relevant to a broad range of RCTs addressing questions of effectiveness for strategies to improve practice and policy in the areas of social determinants of health, clinical care, health systems, public health, and international development, where health and/or access to health care is a primary outcome. The outcomes include a reporting guideline (CONSORT-equity extension) for equity-relevant RCTs and a knowledge translation strategy to broadly encourage its uptake and use by journal editors, authors, and funding agencies.

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How effects on health equity are assessed in systematic reviews of interventions

Welch

Tugwell

Petticrew

et al. 2010

Cochrane Database of Systematic Reviews

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Background Enhancing health equity has now achieved international political importance with endorsement from the World Health Assembly in 2009. The failure of systematic reviews to consider effects on health equity is cited by decision-makers as a limitation to their ability to inform policy and program decisions. Objectives To systematically review methods to assess effects on health equity in systematic reviews of effectiveness.

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Systematic reviews reveal unrepresentative evidence for the development of drug formularies for poor and nonwhite populations

Cited by 10 publications

References 67 publications

Study sponsorship and the nutrition research agenda: analysis of randomized controlled trials included in systematic reviews of nutrition interventions to address obesity

Study sponsorship and the nutrition research agenda: analysis of randomized controlled trials included in systematic reviews of nutrition interventions to address obesity

Protocol for the development of a CONSORT-equity guideline to improve reporting of health equity in randomized trials

How effects on health equity are assessed in systematic reviews of interventions

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