Systematic review of treatment and prognosis of sinonasal hemangiopericytoma

Abstract

BackgroundThis study was undertaken to determine the recurrence rate for open and endoscopic surgery and the clinical prognosis of this sinonasal tumor.MethodsA systematic review of individual cases of sinonasal hemangiopericytoma was performed. A total of 97 articles were included in the study and reviewed to extract the relevant information about each case.ResultsIn all, 194 cases of sinonasal hemangiopericytoma were identified. There were 53 recurrences (27.3%), 6 tumor‐related deaths (3.1%), and 4 cases of metastases (2.1%). There was no significant difference between rate of recurrence for endoscopic or open resection (p = .06). Incomplete excision was the most important predictor of recurrence (odds ratio = 11.50, 95% confidence interval 3.76–36.82, p < .001). Radiotherapy may be advantageous in cases of incomplete surgical resection (p = .03).ConclusionsComplete excision is essential to minimize tumor recurrence and radiotherapy may decrease the rate of recurrence in the case of incomplete resection. Current evidence does not suggest that open resection is superior to endoscopic resection. © 2012 Wiley Periodicals, Inc. Head Neck, 2013

Endoscopic management of sinonasal hemangiopericytoma: case report and literature review

“…(4) With less than 200 cases of sinonasal hemangiopericytomas reported in the litera-ture, only limited assumptions can be made about the tumor. (10,11) This is another case of sinonasal hemangiopericytoma to add to the small but growing body of literature on this disease. Historically, open surgical methods for tumor extirpation have been considered as standard treatment, although endoscopic resection has increased in recent decades.…”

Nasal Cavity Paraganglioma: Literature Review and Discussion of a Rare Case

“…This presents as a nonhomogeneous soft tissue mass with bone erosion, necrosis, and early-stage intracranial growth [5]. Other highly vascular lesions are hemangioma (exceedingly rare in the nasal cavity and images may show a honey-comb appearance) and hemangiopericytomas (approximately 2.5% of all vascular sinonasal tumors, mostly heterogeneous, with cystic areas and signal-void vessels) [5,42,45,46]. …”

A rare sinonasal tumour with orbital manifestation: glomangiopericytoma

“…12,13 Few studies reports the use of radiotherapy and chemotherapy in cases of inoperable tumors, metastasis or palliative therapy. Limited study data showed that patients receiving radiotherapy following an incomplete surgical resection has lower rate of recurrence.…”

“…Limited study data showed that patients receiving radiotherapy following an incomplete surgical resection has lower rate of recurrence. 12 However, small number of data limits the assessment of its treatment efficacy.…”

“…Long term follow up is required as recurrence has been reported to occur up to 17 years following initial presentation. 12 The role of chemo and radiotherapy remains controversial.…”