Systematic Review of the Cost Effectiveness of Radiation Therapy for Prostate Cancer from 2003 to 2013

Amin, Neha; Sher, David J.; Konski, André

doi:10.1007/s40258-014-0106-9

Cited by 63 publications

(40 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Prior studies have investigated the cost-effectiveness of various prostate cancer treatment modalities. Many of these studies have made comparisons among radiotherapy techniques, including brachytherapy and various radiotherapy techniques such as intensity-modulated radiotherapy (IMRT), stereotactic body radiotherapy (SBRT), and 3D-conformal radiotherapy (17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27). Other studies have focused on comparisons among surgical techniques (28)(29)(30).…”

Section: Discussionmentioning

confidence: 99%

Challenges in the Analysis of Outcomes for Surgical Compared to Radiotherapy Treatment of Prostate Cancer

Glaser

Kalash

Bongiorni

et al. 2018

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Challenges in the Analysis of Outcomes for Surgical Compared to Radiotherapy Treatment of Prostate Cancer

Glaser

Kalash

Bongiorni

et al. 2018

View full text Add to dashboard Cite

show abstract

“…Another study by Amin et al 41 systematically reviewed the literature to identify articles that performed cost-effectiveness analysis of rt options for prostate cancer to identify the main cost drivers. Both studies also found large variations in the cost of rt between studies because of factors unrelated to the patient and the various treatment-related morbidities; however, neither study performed a thorough investigation of differences in costing components and sources in rt.…”

Section: Discussionmentioning

confidence: 99%

Radiation Costing Methods: A Systematic Review

et al. 2016

View full text Add to dashboard Cite

Objective Costs for radiation therapy (rt) and the methods used to cost rt are highly diverse across the literature.To date, no study has compared various costing methods in detail. Our objective was to perform a thorough review of the radiation costing literature to identify sources of costs and methods used.Methods A systematic review of Ovid medline, Ovid oldmedline, embase, Ovid HealthStar, and EconLit from 2005 to 23 March 2015 used search terms such as "radiation," "radiotherapy," "neoplasm," "cost," " cost analysis," and "cost benefit analysis" to locate relevant articles. Original papers were reviewed for detailed costing methods. Cost sources and methods were extracted for papers investigating rt modalities, including three-dimensional conformal rt (3D-crt), intensity-modulated rt (imrt), stereotactic body rt (sbrt), and brachytherapy (bt). All costs were translated into 2014 U.S. dollars. ResultsMost of the studies (91%) reported in the 33 articles retrieved provided rt costs from the health system perspective. The cost of rt ranged from US$2,687.87 to US$111,900.60 per treatment for imrt, followed by US$5,583.28 to US$90,055 for 3D-crt, US$10,544.22 to US$78,667.40 for bt, and US$6,520.58 to US$19,602.68 for sbrt. Cost drivers were professional or personnel costs and the cost of rt treatment. Most studies did not address the cost of rt equipment (85%) and institutional or facility costs (66%). ConclusionsCosting methods and sources were widely variable across studies, highlighting the need for consistency in the reporting of rt costs. More work to promote comparability and consistency across studies is needed.

show abstract

“…and gastrointestinal, among others, and has not been shown to be consistently cost effective (31)(32)(33). However, there are no previous studies examining the cost effectiveness of IMRT in the treatment of NSCLC.…”

Section: Original Researchmentioning

confidence: 99%

Cost of Intensity-modulated Radiation Therapy for Older Patients with Stage III Lung Cancer

et al. 2016

View full text Add to dashboard Cite

Rationale: In the treatment of stage III non-small cell lung cancer (NSCLC), three-dimensional conformal radiotherapy (3D-RT) is the standard method for radiation delivery; however, intensitymodulated radiotherapy (IMRT) has been rapidly adopted. These two modalities may lead to similar survival, warranting a closer scrutiny of the costs involved.Objectives: The purpose of this study is to compare radiotherapyrelated and total costs of older patients with NSCLC treated with 3D-RT versus IMRT. Measurements and Main Results: Of the 2,418 patients in study, 314 (13%) received IMRT. Adjusted analyses showed no difference in overall survival (hazard ratio, 0.97; 95% confidence interval [CI], 0.85-1.12) in patients treated with 3D-RT versus IMRT. After adjusting for propensity scores, RT-related costs (estimated difference, $6,850; 95% CI, $5,532-$8,168) and total costs (estimated difference, $8,713; 95% CI, $4,376-$13,051) were significantly higher among patients undergoing IMRT. Conclusions:The rapid adoption of IMRT for the treatment of stage III NSCLC has occurred in the absence of evidence from prospective randomized trials. Our results show that IMRT is associated with similar survival but increased costs, underscoring the need for continued research in IMRT and other new technologies.

show abstract

Systematic Review of the Cost Effectiveness of Radiation Therapy for Prostate Cancer from 2003 to 2013

Cited by 63 publications

References 41 publications

Challenges in the Analysis of Outcomes for Surgical Compared to Radiotherapy Treatment of Prostate Cancer

Challenges in the Analysis of Outcomes for Surgical Compared to Radiotherapy Treatment of Prostate Cancer

Radiation Costing Methods: A Systematic Review

Cost of Intensity-modulated Radiation Therapy for Older Patients with Stage III Lung Cancer

Contact Info

Product

Resources

About