Systematic review of soy isoflavone supplements on osteoporosis in women

Pan, Wei Ren; Liu, Ming; Chen, Yan; Chen, Decai

doi:10.1016/s1995-7645(12)60033-9

Cited by 146 publications

(96 citation statements)

References 28 publications

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“…A previous study indicated that estrogen use increases the performance on certain tests of cognition, particularly in postmenopausal women (20). Short-term high-dose soy bean intake altered the levels of total plasma testosterone and improved spatial cognition in women (24).…”

Section: Effects Of Soy Isoflavones On Learning and Memorymentioning

confidence: 94%

“…Natural or surgical menopause results in an initial phase of rapid bone loss followed by a period of slower skeletal deterioration (19). This rapid phase of bone loss occurs within the first 10 years following the cessation of menses or surgical removal of the ovaries (20). The ovarian hormone deficiency associated with menopause results in an increased rate of bone turnover and leads to an imbalance between resorption and formation, thereby accelerating bone loss (21).…”

Section: Osteoporosis and Soy Isoflavonesmentioning

confidence: 99%

“…A sensitivity analysis indicated that the effect of soy isoflavones on bone mineral density and deoxypyridinoline was significant. Postmenopausal women experience a sharp decrease in estrogen concentration, leading to an increased rate of bone remodeling, which is associated with decreased bone mineral density and increased risk of fractures (20,22,23).…”

Section: Osteoporosis and Soy Isoflavonesmentioning

confidence: 99%

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Soy isoflavone: The multipurpose phytochemical (Review)

Wang¹,

Ge²,

et al. 2013

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Abstract. Soy isoflavones are compounds found in soybean and soybean products. They have been reported to possess numerous physiological properties, such as antitumor, antimenopausal (female) osteoporosis and anti-aging. They have also been reported to improve learning and memory skills in menopausal women and aid in the prevention and treatment of heart disease, diabetes and Kawasaki disease (KD). In this review, the effects of soy isoflavones on various diseases were analyzed. Based on the analysis, it was hypothesized that the function of soybean isoflavones in the prevention and treatment of various diseases results from their phytoestrogen and antioxidant properties. However, due to their phytoestrogen properties, it is recommended that the risks of soy isoflavone intake as food and̸or medical treatment be further evaluated.

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Section: Effects Of Soy Isoflavones On Learning and Memorymentioning

confidence: 94%

Section: Osteoporosis and Soy Isoflavonesmentioning

confidence: 99%

Section: Osteoporosis and Soy Isoflavonesmentioning

confidence: 99%

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Soy isoflavone: The multipurpose phytochemical (Review)

Wang¹,

Ge²,

et al. 2013

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“…Sabe-se que a perda de massa óssea está relacionada com a idade e é maior em mulheres do que em homens. A deficiência hormonal quando associada com os efeitos da menopausa, causa um aumento da taxa de remodelação óssea, provocando um desequilíbrio entre a reabsorção e formação, o que acelera a perda óssea [19,32].…”

Section: Benefícios Do Consumo De Produtos à Base De Sojaunclassified

“…A relação entre as isoflavonas de soja e o tecido ósseo tem sido estudada há pouco menos de dez anos, dados obtidos através de diversos estudos com animais demonstraram que as isoflavonas de soja possuem efeitos de conservação óssea na retenção de massa óssea após ovariectomia [32]. O possível papel desempenhado pelas isoflavonas de soja na modificação de massa óssea humana é de que os suplementos de proteína de soja enriquecidos com isoflavonas atenuam a perda óssea na pós-menopausa e também na pré-menopausa em mulheres.…”

Section: Benefícios Do Consumo De Produtos à Base De Sojaunclassified

Benefícios à saúde humana do consumo de isoflavonas presentes em produtos derivados da soja

Zakir

Freitas

2015

J. Bioen. Food Sci.

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As leguminosas utilizadas na alimentação de diversas populações ao redor do mundo são importantes fontes de energia e diversos nutrientes. A soja (Glycine max) que apresenta uma composição quase completa, vem se destacando como um alimento funcional, pois além de sua função normal de nutrição, ainda apresenta diversos benefícios para a saúde. O grão de soja possui os compostos bioativos que estão sendo amplamente estudados, pois visam a prevenção e a redução dos riscos de desenvolvimento de d oenças crônicas como diabetes, colesterol, hipertensão arterial, cânceres entre outros. As isoflavonas são compostos químicos pertencentes à classe dos fitoestrógenos, as principais isoflavonas encontradas na soja são a daidzeína, a genisteína e a gliciteína. Evidências científicas sugerem que as isoflavonas, desempenham um papel importante na prevenção e controle de doenças crônicas. Devido ao crescente interesse da população em consumir alimentos saudáveis, a indústria alimentícia vem se dedicando a desenvolver novos produtos, cujas funções pretendem ir além do fornecimento dos nutrientes básicos à alimentação humana, esses alimentos são conhecidos como alimentos funcionais. Dessa forma torna-se importante o estudo dos benefícios que o consumo de diferentes produtos alimentícios à base de soja pode oferecer na prevenção e no controle de diversas patologias. O presente trabalho tem como objetivo incentivar o consumo dos produtos derivados de soja, devido aos efeitos benéficos que a ação das isoflavonas presente na leguminosa oferece ao organismo humano. Benefits to human health in consumption of isoflavones present in soybean products ABSTRACT-The legumes used for feeding the diverse populations around the world are important source of energy and various nutrients. Soybean (Glycine max) which features an almost complete composition, has been highlighted as a functional food due to its many health benefits in addition to its normal function of nutrition. The soybean has bioactive compounds that are being widely studied for preventing and reducing chronic disease development risks such as diabetes, cholesterol, hypertension, cancers and others. Isoflavones are chemical compounds belonging to the class of phytoestrogens. The main isoflavones found in soy are daidzein, genistein and glycitein. Scientific evidence suggests that isoflavones play an important role in the prevention and control of chronic diseases. Due to the growing interest of the population to consume healthy foods, the food industry has been dedicated to developing new products whose functions aim to go beyond the provision of basic nutrients for human consumption; these foods are known as functional foods. Thus it becomes important to study the benefits that consumption of different food products soy can offer in the prevention and control of various pathologies. The present study aims to encourage the consumption of soybeans and its derivatives, due to the beneficial effects as the action of isoflavones present in legume provides the human body. Index terms:...

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