Systematic review of laryngeal reinnervation techniques

Abstract

Reinnervation is effective in the management of UVFP, although the specific method may be dictated by anatomical limitations. Prospective studies utilizing uniform and consistent outcome parameters are necessary.

Non-Selective Laryngeal Reinnervation for Unilateral Vocal Fold Paralysis

“…The nerve implant technique is the modification of Tucker's technique whereby the nerve ending is implanted directly into the laryngeal muscle. The most common technique reported is nerve-to-nerve anastomosis employing ansacervicalis as the donor nerve as described by Crumley (ansa-RLN) (14). Wang et al (15) had Editorial improved the technique by using the main branch of the ansa cervicalis that has more axons to regenerate to the injured RLN instead of ansa hypoglossi to sternohyoid, and they described details of the surgery for a successful reinnervation.…”

“…A systematic review of studies on reinnervation in UVFP patients was done to investigate the effectiveness in improving the voice (14). The authors extracted 14 papers out of 686 papers retrieved from literature databases that met the inclusion and exclusion criteria.…”

Optimal Management of Acute Recurrent Laryngeal Nerve Injury During Thyroidectomy

“…Because of this, a tension-free anastomosis is nearly always possible. The ANSA has a diameter similar to that of the RLN and can be used for both ipsilateral and contralateral anastamosis [12,20,21]. The Fig.…”

“…Aynehchi et al [21] systematically reviewed the outcomes from 14 case series of laryngeal reinnervation procedures for unilateral vocal fold paralysis between 1966 and 2009. Owing to the heterogeneity of the available literature and difficulty in analyzing techniques and outcomes, it is difficult to extrapolate direct data comparing different techniques.…”

Histological Organization is Similar in Human Vocal Muscle and Tongue—A Study of Muscles and Nerves

“…12 This technique provides positive effects on vocal fold paralysis in terms of acoustic, perceptual, electromyographic, and visual outcomes. 13 Gathering data on the morphometric features of the RLN and XII is certainly very important for understanding and improving the techniques used for vocal fold reinnervation (XII-to-RLN anastomosis). There are some data on this topic in the literature.…”