Systematic Review of Acupuncture in Cancer Care: A Synthesis of the Evidence

Garcia, M. Kay; McQuade, Jennifer L.; Haddad, Robin; Patel, Sonya; Lee, Richard; Yang, Peiying; Palmer, J. Lynn; Cohen, Lorenzo

doi:10.1200/jco.2012.43.5818

Cited by 272 publications

(203 citation statements)

References 48 publications

Supporting

Mentioning

181

Contrasting

Unclassified

Order By: Relevance

“…Acupuncture, a component of the centuries old traditional Chinese medicine paradigm (1), has shown promise among patients with cancer for treatment of toxicities such as nausea, fatigue, and pain (2). To build a strong evidence base for acupuncture in survivorship care, large randomized controlled trials are needed to establish the efficacy of acupuncture for symptom management in cancer (2).…”

Section: Resultsmentioning

confidence: 99%

“…To build a strong evidence base for acupuncture in survivorship care, large randomized controlled trials are needed to establish the efficacy of acupuncture for symptom management in cancer (2). While acupuncture has been found to be more effective than standard care or usual care in many large RCTs for chronic pain in noncancer populations, the large effect seen in the sham acupuncture (SA) group introduces great uncertainty in evaluating and interpreting the efficacy of acupuncture in the randomized setting (3).…”

Section: Resultsmentioning

confidence: 99%

“…Acupuncture holds tremendous potential to improve symptoms (eg, pain, fatigue, hot flashes) in cancer survivors (2). Despite such promise, larger and more definitive trials with methodological rigor are required to establish both the short and long-term efficacy and effectiveness of acupuncture (2).…”

Section: Implications Of Acupuncture Research For Cancer Survivorshipmentioning

confidence: 99%

“…Despite such promise, larger and more definitive trials with methodological rigor are required to establish both the short and long-term efficacy and effectiveness of acupuncture (2). Randomized trials should measure expectancy using a validated instrument at the beginning and longitudinally to understand the role of expectancy on outcomes (12).…”

Section: Implications Of Acupuncture Research For Cancer Survivorshipmentioning

confidence: 99%

See 3 more Smart Citations

Expectancy in Real and Sham Electroacupuncture: Does Believing Make It So?

Bauml

Xie

Farrar

et al. 2014

JNCMON

View full text Add to dashboard Cite

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Implications Of Acupuncture Research For Cancer Survivorshipmentioning

confidence: 99%

Section: Implications Of Acupuncture Research For Cancer Survivorshipmentioning

confidence: 99%

See 2 more Smart Citations

Expectancy in Real and Sham Electroacupuncture: Does Believing Make It So?

Bauml

Xie

Farrar

et al. 2014

JNCMON

View full text Add to dashboard Cite

show abstract

“…Akupunkturun kanser ve kanser tedavisine bağlı bulantı ve kusmadaki etkisinin değerlendirildiği bazı çalışmalarda olumsuz sonuçlar elde edilse de, olumlu sonuçların alındığı çalışmalar ağırlıktadır (17). Yapılan bir çalışmada akupressör bilek bantlarının bulantı ve kusmayı azalttığı, bu semptomlar için ilaç kullanımı ihtiyacını azalttığı gösterilmiştir (18).…”

Section: Akupunktur Ve Bulantı -Kusmaunclassified

Acupuncture and Cancer

Ünlü¹,

Kirca²,

Duman³

et al. 2017

Akd Med J

View full text Add to dashboard Cite

ÖzAkupunktur, farklı yöntemlerle vücudun belirli noktaları ve buralardan geçen sinirlerin uyarıldığı ve birtakım semptomlarda rahatlama sağlandığı bir tamamlayıcı ve alternatif tıp yöntemidir. Geleneksel Çin Tıbbı'nda akupunkturun etki mekanizması, enerji akımı gibi bilimsel olmayan temellere dayandırılsa da; yapılan çalışmalarla akupunkturun etkisinin sinirlerin uyarılmasıyla salınan maddeler ve plasebo etkisine dayandığı gösterilmiştir. Akupunktur, kanser hastalarının da sıkça başvurduğu bir yöntemdir. Ancak akupunkturun kanserde tek başına etkin bir tedavi yöntemi olduğuna dair bilimsel bir kanıt yoktur. Kanser hastaları, akupunktur yöntemini kansere ve/veya kanser tedavisine bağlı belirtilerde azalma sağlamak amacıyla, standart tedaviye ek olarak tamamlayıcı bir tedavi yöntemi olarak kullanabilir. Yapılan çalışmalarla; akupunkturun kanser hastalarında ağrı, halsizlik, bulantı, kusma, psikolojik problemler, ağız kuruluğu, lenfödem, lökopeni, sıcak basmaları, duyu bozuklukları, nefes darlığı semptomlarında rahatlama sağlayabileceğine yönelik bulgular elde edilse de, yeterli değildir. Akupunkturun kanser hastalarındaki etkileri ve kullanım alanlarına dair, yapılacak kapsamlı ve iyi tasarlanmış çalışmalara ihtiyaç vardır.Anahtar Sözcükler: Akupunktur, Kanser, Alternatif tıp, Tamamlayıcı tıp AbStrActAcupuncture is a complementary and alternative medical method, helpful in relieving certain symptoms, that involves stimulating certain points on the body as well as nerves passing though those points, with the use of various techniques. Although the mechanism of action of acupuncture is based on some unscientific foundations such as energy flow in Traditional Chinese Medicine, studies have shown that the effect of acupuncture is based on the placebo effect and the substances released in consequence of the stimulation of the nerves. Acupuncture is a method that is often tried by cancer patients. However, there is no scientific evidence showing that acupuncture alone is an effective treatment for cancer. Cancer patients should use acupuncture technique as a complementary treatment in addition to the standard treatment, with intent to ensure a reduction in symptoms caused by cancer and/or cancer treatment. Some findings obtained from studies have suggested that acupuncture can provide relief from some symptoms such as pain, fatigue, nausea, vomiting, psychological problems, dryness of the mouth (xerostomia), lymphedema, leukopenia, hot flashes, sensory impairment, and shortness of breath in cancer patients; however, these findings are not adequate. Comprehensive and well-designed studies to be carried out on the effects of acupuncture in cancer patients as well as its areas of use are needed.

show abstract

Clinical Evidence for Association of Acupuncture and Acupressure With Improved Cancer Pain

et al. 2020

View full text Add to dashboard Cite

IMPORTANCE Research into acupuncture and acupressure and their application for cancer pain has been growing, but the findings have been inconsistent. OBJECTIVE To evaluate the existing randomized clinical trials (RCTs) for evidence of the association of acupuncture and acupressure with reduction in cancer pain.DATA SOURCES Three English-language databases (PubMed, Embase, and CINAHL) and 4 Chinese-language biomedical databases (Chinese Biomedical Literature Database, VIP Database for Chinese Technical Periodicals, China National Knowledge Infrastructure, and Wanfang) were searched for RCTs published from database inception through March 31, 2019.STUDY SELECTION Randomized clinical trials that compared acupuncture and acupressure with a sham control, analgesic therapy, or usual care for managing cancer pain were included.DATA EXTRACTION AND SYNTHESIS Data were screened and extracted independently using predesigned forms. The quality of RCTs was appraised with the Cochrane Collaboration risk of bias tool. Random-effects modeling was used to calculate the effect sizes of included RCTs. The quality of evidence was evaluated with the Grading of Recommendations Assessment, Development and Evaluation approach.MAIN OUTCOMES AND MEASURES The primary outcome was pain intensity measured by the Brief Pain Inventory, Numerical Rating Scale, Visual Analog Scale, or Verbal Rating Scale. RESULTS A total of 17 RCTs (with 1111 patients) were included in the systematic review, and data from 14 RCTs (with 920 patients) were used in the meta-analysis. Seven sham-controlled RCTs (35%) were notable for their high quality, being judged to have a low risk of bias for all of their domains, and showed that real (compared with sham) acupuncture was associated with reduced pain intensity (mean difference [MD], −1.38 points; 95% CI, −2.13 to −0.64 points; I 2 = 81%). A favorable association was also seen when acupuncture and acupressure were combined with analgesic therapy in 6 RCTs for reducing pain intensity (MD, −1.44 points; 95% CI, −1.98 to −0.89; I 2 = 92%) and in 2 RCTs for reducing opioid dose (MD, −30.00 mg morphine equivalent daily dose; 95% CI, −37.5 mg to −22.5 mg). The evidence grade was moderate because of the substantial heterogeneity among studies. CONCLUSIONS AND RELEVANCEThis systematic review and meta-analysis found that acupuncture and/or acupressure was significantly associated with reduced cancer pain and decreased use of analgesics, although the evidence level was moderate. This finding suggests that more rigorous trials are needed to identify the association of acupuncture and acupressure with specific types of cancer pain and to integrate such evidence into clinical care to reduce opioid use. Research Original InvestigationAssociation of Acupuncture and Acupressure With Improved Cancer Pain 37. Tao WW, Jiang H, Tao XM, Jiang P, Sha LY, Sun XC. Effects of acupuncture, tuina, tai chi, qigong, and traditional Chinese medicine five-element music therapy on symptom management and quality of life for cancer patients: a meta...

show abstract

Systematic Review of Acupuncture in Cancer Care: A Synthesis of the Evidence

Cited by 272 publications

References 48 publications

Expectancy in Real and Sham Electroacupuncture: Does Believing Make It So?

Expectancy in Real and Sham Electroacupuncture: Does Believing Make It So?

Acupuncture and Cancer

Clinical Evidence for Association of Acupuncture and Acupressure With Improved Cancer Pain

Contact Info

Product

Resources

About