Systematic review and Meta-analysis of treating open angle glaucoma with gonioscopy-assisted transluminal trabeculotomy

Guo, Chenchen

doi:10.18240/ijo.2020.02.17

Cited by 33 publications

(50 citation statements)

References 18 publications

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“…This step may prevent postoperative hyphema 7. We did not observe any sight-threatening complications in our study, which is consistent with other case series 15…”

Section: Discussionsupporting

confidence: 92%

“…We found postoperative hyphema in 39% of eyes, with a median duration of 5 days. Similarly, the pooled occurrence rate of hyphema was 36% in the meta-analysis conducted by Guo et al 15 The rate of hyphema occurrence, however, may vary in the literature. Loayza-Gamboa et al, 25 studying outcomes of PHACO-GATT, saw the transient presence of blood in the anterior chamber in only 9.3% of the eyes.…”

Section: Discussionmentioning

confidence: 85%

“…In a 24-month outcomes publication, Sharkawi et al14 revealed a success rate of 89.2% in eyes with pseudoexfoliative glaucoma. Guo et al,15 in a recently published meta-analysis, found a combined surgical success rate of 85% (with a more pronounced reduction in the subgroup of studies with a follow-up longer than 12 mo).…”

Section: Discussionmentioning

confidence: 99%

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Gonioscopy-Assisted Transluminal Trabeculotomy for Glaucoma: 1-Year Outcomes and Success Predictors

Faria

Costa

Melillo

et al. 2022

Journal of Glaucoma

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Précis: Our results suggest gonioscopy-assisted transluminal trabeculotomy (GATT) as an effective and safe option for the surgical management of open-angle glaucoma (OAG). Older age was the only risk factor for failure in our analysis. Purpose: To report 12-month clinical outcomes, safety profile and success predictors of GATT in patients with OAG. Patients and Methods: A retrospective study of patients (18 y old and above) with medically uncontrolled OAG who underwent GATT as a solo procedure or combined with phacoemulsification (PHACO-GATT) between January 2018 and January 2020. Success at 12 months (primary outcome) was defined as intraocular pressure (IOP) <15 mm Hg, with an IOP reduction of at least 20%, OR a reduction of at least 2 glaucoma medications, compared with baseline. Secondary outcomes were success predictors and safety parameters. Results: A total of 73 eyes (GATT=38; PHACO-GATT=35) from 58 patients with a mean age of 54.8±11.6 years were included. Overall, after 12 months of follow-up, the mean IOP was reduced from 24.9±8.5 to 12.1±2.1 mm Hg (P<0.001). The mean number of glaucoma medications was reduced from 3.5±0.7 to 1.2±1.2 (P<0.001). The success rate was 87% at 12 months, with no significant differences between GATT (85%) and PHACO-GATT (91%) eyes (P=0.330). Age was the only factor significantly associated with surgical success (hazard ratio=1.35; P=0.012; after adjusting for preoperative IOP and number of glaucoma medications). Patients older than 60 years had a significant greater chance of failure (hazard ratio=10.96; P=0.026) compared with those younger than 60 years. The most common postoperative complication was transient hyphema (39%; median duration, 5 d). No sight-threatening adverse event was documented. Conclusions: GATT was effective and safe at lowering IOP with or without cataract extraction in OAG. Patients 60 years or older had a higher risk of failure compared with those younger in age.

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“…This step may prevent postoperative hyphema 7. We did not observe any sight-threatening complications in our study, which is consistent with other case series 15…”

Section: Discussionsupporting

confidence: 92%

Section: Discussionmentioning

confidence: 85%

See 1 more Smart Citation

Gonioscopy-Assisted Transluminal Trabeculotomy for Glaucoma: 1-Year Outcomes and Success Predictors

Faria

Costa

Melillo

et al. 2022

Journal of Glaucoma

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“…The most common postoperative complications described in large cohorts of patients treated with GATT are transient hyphema and IOP spikes [ 6 , 8 , 9 , 23 , 24 ]. Rarer complications include panscleritis in a patient with a history of anterior uveitis [ 25 ], postoperative intracapsular hematoma in a pseudophakic patient [ 26 ], and Descemet’s membrane detachment [ 27 ].…”

Section: Discussionmentioning

confidence: 99%

“…Following GATT, the most common complication is transient hyphema, which can occur in up to 100% of patients within the first weeks after surgery [ 8 , 9 ]. Other complications may occur more rarely, including Descemet’s membrane detachment, cyclodialysis cleft, suprachoroidal haemorrhage, vitreous haemorrhage, microcystic corneal edema, postoperative transient intraocular pressure (IOP) spikes, supraciliary effusion and cystoid macular edema [ 8 , 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Malignant glaucoma following gonioscopy-assisted transluminal trabeculotomy: a case report

et al. 2022

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Background To report a case of malignant glaucoma that developed after gonioscopy-assisted transluminal trabeculotomy (GATT). Case presentation An 85-year-old male pseudophakic patient affected by pseudoexfoliative glaucoma (PEXG), unresponsive to medical glaucoma treatment, underwent uneventful GATT surgery. On the first day after surgery, the eye showed a shallow central and peripheral anterior chamber (AC) with a raised intraocular pressure (IOP) measured at 55 mmHg. Optical coherence tomography and ultrasound biomicroscopy confirmed the diagnosis of malignant glaucoma. Laser iridotomy, posterior capsulotomy and hyaloidotomy were performed, and the patient was treated with atropine sulphate 1%, maximum topical and systemic ocular hypotensive drugs with no improvement in the IOP. Subsequently, the patient underwent pars plana anterior vitrectomy, resulting in deepening of the AC with opening of the iridocorneal angle and decrease of the IOP. No further postoperative complications were recorded, and the IOP remained controlled 12 months after surgery without antiglaucoma medications. Conclusions Despite the minimally invasive profile of GATT, malignant glaucoma may develop after this procedure. Early recognition and prompt treatment are mandatory for preventing permanent visual loss.

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Retracted: Prevalence of active trachoma infection and associated factors post‐war resettled population in raya kobo districts, North East Ethiopia: A community‐based cross‐sectional study in 2022

Kebede,

Jamal

2023

Health Science Reports

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BackgroundActive trachoma infection poses a serious threat to public health, particularly for those who live in an unprivileged area and has practiced open‐field defecation. This study aimed to estimate the prevalence of active trachoma infection and associated factors in the post‐war resettled population in Raya Kobo district, North East Ethiopia: a community‐based cross‐sectional study in 2022.MethodsA community‐based cross‐sectional study was conducted among 602 participants randomly selected in 14 slum villages in Raya Kobo from February 16th to March 30th, 2023. After the data was collected using a semi‐structured questionnaire and entered into Epi‐data version 3.2. The study participants were chosen using a two‐stage sampling process. Binary logistic regression was used to identify factors for active trachoma infection. Adjusted odds ratios (AORs) with 95% confidence intervals (CIs) were claimed for the strength of association at p < 0.05.ResultsOverall, 602 (99.9%) study participants were included in the final analysis. At the end of the study period, 126 (20.9) participants developed active trachoma infection. On multivariable analysis, were aged ≥45 years (AOR = 7.9, 95% CI = 2.4–25.3), history of eye infection (AOR = 3.7, 95% CI = 2.4–10.4, p = 0.001), were poor wealth index (AOR = 9.2, 95% CI = 2.7–23.7), having separated kitchen (AOR = 4.05, 95% CI = 1.86–8.86), living with animals (AOR = 5.92, 95% CI = 2.31–14.7) and having got administration of mass‐drug (AOR = 8.9, 95% CI = 2.36–33.6) were significant risk factors for active trachoma infection. Whereas, face washing practice regularly (AOR = 0.23, 95% CI = 0.127–0.43), and toilet availability (AOR = 0.35, 95% CI = 0.20–0.97) were preventive factors for active trachoma infection.ConclusionA significant prevalence of active trachoma infection was reported in the area as compared with previous findings and urgent clinical intervention, and the WHO critical SAFE strategies (surgery, antibiotics, facial cleanliness, and environmental improvement) implementation is highly needed in the area. In addition, healthcare providers should focus on information dissemination on proper latrine utilization, and washing the face regularly to prevent active trachoma infection is highly recommended.

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Systematic review and Meta-analysis of treating open angle glaucoma with gonioscopy-assisted transluminal trabeculotomy

Cited by 33 publications

References 18 publications

Gonioscopy-Assisted Transluminal Trabeculotomy for Glaucoma: 1-Year Outcomes and Success Predictors

Gonioscopy-Assisted Transluminal Trabeculotomy for Glaucoma: 1-Year Outcomes and Success Predictors

Malignant glaucoma following gonioscopy-assisted transluminal trabeculotomy: a case report

Retracted: Prevalence of active trachoma infection and associated factors post‐war resettled population in raya kobo districts, North East Ethiopia: A community‐based cross‐sectional study in 2022

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