Systematic Review and Meta‐Analysis of the Correlates of Cancer‐Related Fatigue

Oh, Hyun Soo; Seo, Wha Sook

doi:10.1111/j.1741-6787.2011.00214.x

Cited by 85 publications

(60 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Cancer patients and their oncologists thus often underestimate the psychological component underlying frequent or multiple reported symptoms and do not consider the potential benefit of using psychological treatments to help manage symptoms. Our findings are in line with previous research (Valentine and Meyers, 2001;Oh and So, 2010) indicating that psychological distress, rather than symptom distress, is likely to be more strongly related to symptoms such as fatigue. This suggests that psychological approaches are likely to be a useful means of management.…”

Section: Discussionsupporting

confidence: 83%

Symptom Prevalence and Related Distress in Cancer Patients Undergoing Chemotherapy

Thiagarajan

Chan²,

et al. 2016

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

Background: Much has been done to examine the psychological impact of cancer treatment, but it remains unclear to what extent anxiety and depression is related to symptom prevalence. The present study concerned the characteristics and frequency of distress as related to symptom prevalence in cancer patients undergoing chemotherapy in Malaysia. Materials and Methods: Participants were 303 consecutive adult cancer patients undergoing chemotherapy in an academic medical center. The short form Memorial Symptom Assessment Scale (MSAS-SF), which covers three domains of symptoms (global distress, physical-and psychological symptoms) was used to cross-sectionally measure symptom frequency and associated distress via self-reporting. One-way ANOVA and t-tests were used to test mean differences among MSAS-SF subscale scores. Results: Complete data were available for 303 patients. The mean number of symptoms was 14.5. The five most prevalent were fatigue, dry mouth, hair loss, drowsiness and lack of appetite. Overall, symptom burden and frequency were higher than in other published MSAS-SF studies. Higher symptom frequency was also found to be significantly related to greater distress in cancer patients undergoing chemotherapy. Conclusions: Patients undergoing chemotherapy suffer from multiple physical and psychological symptoms. Better symptom control or palliative care is needed. Greater frequency of reported symptoms may also indicate a subconscious bid by patients for care and reassurance -thus tailored intervention to manage distress should be offered.

show abstract

Section: Discussionsupporting

confidence: 83%

Symptom Prevalence and Related Distress in Cancer Patients Undergoing Chemotherapy

Thiagarajan

Chan²,

et al. 2016

Asian Pacific Journal of Cancer Prevention

View full text Add to dashboard Cite

show abstract

“…[10][11][12] The majority of breast and colon cancer patients receiving chemotherapy face a variety of symptoms and side effects, including fatigue, pain, anxiety and depression, putting them at risk of further physical, functional and emotional decline during treatment. [12][13][14] Additionally, the literature shows that colon or breast cancer patients undergoing chemotherapy experience a 50% decline in PA compared with prediagnosis. 15 16 To encourage physically inactive patients with cancer not meeting national guidelines (150 min/week regular, moderate PA and 2×20 min/week strenuous exercise 17 18 ) to initiate and increase PA, exploring their perceptions of the recruitment process and perspectives on participation in interventions is essential.…”

Section: Introductionmentioning

confidence: 99%

Rethinking exercise identity: a qualitative study of physically inactive cancer patients’ transforming process while undergoing chemotherapy

et al. 2017

View full text Add to dashboard Cite

ObjectiveTo explore physically inactive breast and colon cancer patients’ prediagnosis exercise history and attitudes to physical activity (PA) and experiences in initiating PA while undergoing adjuvant chemotherapy.DesignAn explorative qualitative study guided the interpretive analysis of semistructured, open-ended interviews conducted at initiation of chemotherapy and after 12 weeks. The study was embedded in a pilot randomised controlled trial.SettingParticipants were recruited from the Oncological Department at a hospital in Copenhagen, Denmark.Participants33 patients with cancer, median age 49 years: 25 patients with breast cancer and 8 with colon cancer, 72% with a low cardiac respiratory fitness level and the majority with a high level of education. Patients received adjuvant chemotherapy, oncologist’s PA recommendation and exercise, cancer nurse specialist’s counselling prior to allocation to PA interventions or waitlist control group.ResultsPrediagnosis exercise had been excluded from patients’ daily lives due to perceptions of exercise as boring, lack of discipline and stressful work conditions for both genders. Recommendations from oncologists and nurses inspired the patients to reconsider their attitudes and behaviour by accepting recruitment and participation in PA interventions during chemotherapy. Despite extensive side effects, most patients adhered to their PA commitment due to their perception of the bodily, emotional and social benefits and support of healthcare professionals, peers and family.ConclusionThe patients’ attitude towards exercise transformed from having no priority in patients’ daily lives prediagnosis to being highly prioritised. This study identified four important phases in the exercise transformation process during the patients’ treatment trajectory of relevance to clinicians in identifying, motivating and supporting physically inactive patients with cancer at long-term risk. Clinicians should address young, highly educated patients with cancer at onset of adjuvant chemotherapy due to their specific risk of a sedentary lifestyle resulting from being in stressful, ambitious careers.Trial registration numberCurrent Controlled Trials (ISRCTN24901641), Stage: Qualitative results.

show abstract

“…Second, symptom management and QOL researchers, for the most part, worked in a relative vacuum and lacked expertise in the development and testing of biomarkers based on molecular mechanisms. However, as the underlying mechanisms for the most common symptoms experienced by cancer patients and survivors (i.e., pain, 4 fatigue, 5,6 sleep disturbance, 7-9 depression 10-12 ) are being elucidated through studies in both animals and humans, the need to identify clinically relevant biomarkers for individual symptoms and symptom clusters, 13-15 as well as QOL outcomes has become a scientific imperative.…”

Section: Introductionmentioning

confidence: 99%

Biomarkers: Symptoms, Survivorship, and Quality of Life

Miaskowski¹,

Aouizerat²

2012

Seminars in Oncology Nursing

View full text Add to dashboard Cite

Objectives To review the evidence on a number of biomarkers that show potential clinical utility in the prediction of and treatment responsiveness for the four most common symptoms associated with cancer and its treatment (i.e., pain, fatigue, sleep disturbance, depression). Data Sources Review and synthesis of review articles and data-based publications. Conclusions A growing body of evidence suggests that sensitive and specific biomarkers will be available to assist clinicians with the assessment and management of symptoms. Implications for Practice Nurses will play a critical role in educating patients about their risk for specific symptoms based on an evaluation of specific biomarkers. Nurses will be involved in using biomarker data to titrate medications based on patient’s responses to symptom management interventions.

show abstract

Systematic Review and Meta‐Analysis of the Correlates of Cancer‐Related Fatigue

Cited by 85 publications

References 50 publications

Symptom Prevalence and Related Distress in Cancer Patients Undergoing Chemotherapy

Symptom Prevalence and Related Distress in Cancer Patients Undergoing Chemotherapy

Rethinking exercise identity: a qualitative study of physically inactive cancer patients’ transforming process while undergoing chemotherapy

Biomarkers: Symptoms, Survivorship, and Quality of Life

Contact Info

Product

Resources

About