SYSTEMATIC REVIEW & META-ANALYSIS OF COMPARATIVE STUDY BETWEEN SAPHENOUS VEIN AND RADIAL ARTERY AS A CONDUIT IN CORONARY ARTERY BYPASS GRAFTING SURGERY

Abstract

Background:The cornerstone of contemporary coronary artery surgery is the testing and standardization of many grafts, which has ushered in the age of evidence-based cardiac surgery. Multiple conduits are utilized, but the left internal mammary artery to the left anterior descending artery is the gold standard. While the second conduit's selection is still debatable. Aim of the work: to compare by Meta-analysis study the difference between Radial Artery (RA) & Saphenous vein (SV) as second conduits in CABG regarding long-term patency, mortality & morbidity.Subjects & Methods: We included data from 15 cohort and case matched studies with a total of 78,267 patients and an average followup of 8.25 years in this analysis. Using Comprehensive Meta-Analysis software, we performed paired meta-analyses of our outcomes (CMA version 3.9). Results:In our study, we found that the using of saphenous vein during CABG had a higher complete graft occlusion/stenosis rate, myocardial infarction rate, mortality rate, stroke rate, major adverse cardiac events (MACE) rate than the using of Radial artery. While the using of radial artery during CABG had a higher patency rate, percutaneous coronary intervention rate, coronary surgery repetition rate than the using of saphenous vein. Conclusion:These results indicate that the radial artery has long-term beneficial & improving post-operative outcomes rather than the saphenous vein.