Systematic Oscillations of Serum Biochemic and Hematologic Parameters in Sinclair(S-1) Miniature Swine

Tumbleson, M. E.; Badger, Thomas M.; Baker, Patricia C.; Hutcheson, D. P.

doi:10.2527/jas1972.35148x

Cited by 8 publications

(4 citation statements)

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“…It has been shown that the stress response associated with chemical or physical restraint may influence hematology and serum chemistry variables . Thereby, acute stress associated with physical struggling or snare restraint and application of anesthetic agents induced marked changes in a series of hematologic and biochemical variables .…”

Section: Discussionmentioning

confidence: 99%

Hematologic and biochemical reference intervals for Wild Boar (Sus scrofa) captured by cage trap

Casas-Díaz

Closa‐Sebastià

Marco

et al. 2015

Veterinary Clinical Pathol

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Background Establishing reference intervals (RI) for hematologic and biochemical variables in wild animals presents great challenges because capture stress or anesthesia during sampling can affect blood variables. Objectives The aims of this study were to establish RI for hematologic and blood biochemistry variables for Wild Boar (Sus scrofa) caught using cage traps, and provide information on the studied variables for different age groups. Methods Blood samples were obtained from 89 Wild Boars captured by cage trap between 2005 and 2013 in northeastern Spain. Piglets were handled without anesthesia, while juvenile and adult animals were anesthetized using a combination of tiletamine and zolazepam. Blood samples were collected from the anterior vena cava and were placed into plain and EDTA tubes. Thirteen hematologic and 21 biochemical variables were determined. Reference intervals for piglets and juvenile and adult groups were determined, and differences between these groups were statistically analyzed. Results Adults had higher HGB, PCV, MCH, MCHC, neutrophil count, and total protein, albumin, creatinine, and chloride concentrations than juveniles; in contrast, juveniles had higher values for lymphocyte count, cholesterol concentration, and ALP activity. Conclusions Reference intervals determined in this study provide a baseline for interpreting hematologic and biochemical results in Wild Boar at different age stages, and contribute to optimization of the management of this species.

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Section: Discussionmentioning

confidence: 99%

Hematologic and biochemical reference intervals for Wild Boar (Sus scrofa) captured by cage trap

Casas-Díaz

Closa‐Sebastià

Marco

et al. 2015

Veterinary Clinical Pathol

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“…are not yet widely used in life science research and one possible reason is the lack of reference values [14]. In this study, we provided useful reference values of Microminipigs, and thereby it would facilitate the use Microminipigs in various life science researches.…”

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confidence: 99%

“…Because of their physiological and anatomical similarities to humans [5], swine are becoming increasingly attractive animal models in toxicological and pharmacological research. Recently, minipigs defined that they are smaller than domestic swine and their body weight (BW) is <100 kg, have been developed including the strains of Göttingen, Yucatan, Sinclair, Clawn, and others [2,9,14]. However, most minipigs are difficult to manage due to their large size, e.g.…”

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confidence: 99%

Reference Values of Hematological and Biochemical Parameters for the World Smallest Microminipigs

et al. 2012

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“…They found an increasing tendency of PCV from birth until 8 weeks of age. Tumbleson et al (1972) and Buck (1975) found only non-significant oscillation in PCV values from birth to week 7 of age and their maximum values were not higher than 0.38 l/l. Similar results reported also Becker et al (1976) and Wrogemann and Holtz (1977) in Göttingen minipigs.…”

Section: Discussionmentioning

confidence: 94%

Development of Haematological Indices in Melanoma-bearing Liběchov Minipigs

Svoboda¹,

Eichlerová²,

Horák³

et al. 2005

Acta Vet. Brno

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The aim of the study was to investigate the development of haematological indices in the MeLiM strain of miniature pigs. MeLiM minipigs in group M were affected with hereditary malignant melanoma and received 100 mg Fe 3+ dextran i.m. on day 3 of age. Group H contained melanomafree MeLiM minipigs that were supplemented with iron as in group M. Melanoma-free MeLiM minipigs without iron supplementation till the week 5 of age were included in group A. Development of haematological indices in group H was compared to literature data from other breeds and strains of minipigs. Red blood cell indices in group A were found to be characteristic for hypochromic microcytary anaemia. Higher red blood cell counts were found in animals affected with melanoma (group M) on week 8 of age compared to group H. Pigs in group M showed also lower growth intensity compared to healthy animals (group H).Hereditary melanoma, MeLiM, haemoglobin, packed cell volume, iron

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Systematic Oscillations of Serum Biochemic and Hematologic Parameters in Sinclair(S-1) Miniature Swine

Cited by 8 publications

References 0 publications

Hematologic and biochemical reference intervals for Wild Boar (Sus scrofa) captured by cage trap

Hematologic and biochemical reference intervals for Wild Boar (Sus scrofa) captured by cage trap

Reference Values of Hematological and Biochemical Parameters for the World Smallest Microminipigs

Development of Haematological Indices in Melanoma-bearing Liběchov Minipigs

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