2006
DOI: 10.1007/s00464-004-2231-2
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Systematic evaluation of different approaches for minimizing hemodynamic changes during pneumoperitoneum

Abstract: Optimizing volume load is effective for minimizing hemodynamic changes during CP in the head-up and in head-down positions. In general, beta(1)-blockers cannot be recommended because they might additionally compromise myocardial contractility and suppress compensatory reaction of the sympathetic nerve system. Vasodilation has not improved hemodynamic parameters during CP.

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Cited by 19 publications
(15 citation statements)
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References 23 publications
(23 reference statements)
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“…Due to the harmful effects of elevated IAP, it is recommended that the lowest IAP possible be used, allowing adequate exposure of the operative field, rather than a standard pressure [17]. To counteract diminished organ perfusion and decreased cardiac function, generous volume loading is recommended [8,17]. To minimize these harmful effects, we used a low IAP (8)(9)(10)(11)(12) for patients with pneumoperitoneum.…”
Section: Discussionmentioning
confidence: 98%
“…Due to the harmful effects of elevated IAP, it is recommended that the lowest IAP possible be used, allowing adequate exposure of the operative field, rather than a standard pressure [17]. To counteract diminished organ perfusion and decreased cardiac function, generous volume loading is recommended [8,17]. To minimize these harmful effects, we used a low IAP (8)(9)(10)(11)(12) for patients with pneumoperitoneum.…”
Section: Discussionmentioning
confidence: 98%
“…In a previous manuscript, we have already shown that an increased ITBV improves hemodynamic function in all body positions during PN [6]. The selective β-blocker esmolol reduced cardiac output and myocardial contractility.…”
Section: Discussionmentioning
confidence: 99%
“…Several literature reports based on laboratory and clinical parameters have given controversial results concerning hemodynamic changes as well as endocrine responses during PN [1,2,3]. Treatments with clonidine, β-blockers, sodium nitroprusside and intravenous administration of fluid were tested to eliminate negative hemodynamic effects of PN in various animal studies [4,5,6]. …”
Section: Introductionmentioning
confidence: 99%
“…Increasing the intrathoracic blood volume improved hemodynamic function in all body positions with pneumoperitoneum. Fluid management is the most important element for minimizing pneumoperitoneum side efects [54].…”
Section: Complicationsmentioning
confidence: 99%