Syringocystadenocarcinoma Papilliferum: Successfully Treated With Mohs Micrographic Surgery

Chi, Ching‐Chi; Tsai, Ren‐Yeu; Wang, Shuhui

doi:10.1111/j.1524-4725.2004.30023.x

Cited by 32 publications

(35 citation statements)

References 12 publications

(36 reference statements)

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“…Although SCAP is frequently encountered clinically, SCACP is rarely observed and its clinical and histologic characteristics are not well known. Only eight cases of SCACP have been reported in the literature (3-8) (Table 1). The male (n=4)-to-female (n=4) ratio was 1:1.…”

Section: Discussionmentioning

confidence: 99%

“…Cells of the inner layer have columnar with oval nuclei and abundant eosinophilic cytoplasm and decapitation on the luminal surface, while the cells of the outer layer are small, cuboidal of flattened and have scanty cytoplasm and oval nuclei. Stroma of the tumor contains a dense inflammatory infiltrate, composed of numerous plasma cells and lymphoid cells (8). Occasionally, numerous normal apocrine glands can be found.…”

Section: Discussionmentioning

confidence: 99%

“…Occasionally, numerous normal apocrine glands can be found. However, SCACP can be different from SCAP in that it has an asymmetric structure of tumor and the boundary is not clear; often tumor cells infiltrate the deep dermis or subcutaneous fat in tubular, cystic or solid types; neoplastic cells exhibit crowed nuclei, variable degrees of nuclear atypia, and numerous mitotic figures (2, 8). From the above figdings, SCACP can be considered malignant.…”

Section: Discussionmentioning

confidence: 99%

“…They lack papillary structures containing deep invaginations as seen in SCACP. Metastatic thyroid carcinoma and hidradenoma papilliferum should also be included in the differential diagnosis due to their papillary structures (8). …”

Section: Discussionmentioning

confidence: 99%

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Syringocystadenocarcinoma Papilliferum: A Case Report

Park

Shin

et al. 2007

J Korean Med Sci

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Syringocystadenocarcinoma papilliferum (SCACP) is a rare form of adenocarcinoma of the skin. This is the malignant counterpart of syringocystadenoma papilliferum (SCAP) and usually develops on the scalp in a long-standing lesion identified clinically as SCAP. We describe a 65-yr-old Korean man with a nodule on the right supra-pubic area with a 2-yr duration. Histologically this tumor had a similar overall configuration as in SCAP, but the tumor was asymmetric and poorly circumscribed, extending into the deep dermis and showed cytologic atypia. The tumor cells showed positive reaction to GCDFP-15, but negative reaction to CEA and HMFG-1. We established the diagnosis of SCACP in the patient, and a wide excision was performed to remove the tumor. The patient has been well without relapse or metastasis for 2 yr.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Syringocystadenocarcinoma Papilliferum: A Case Report

Park

Shin

et al. 2007

J Korean Med Sci

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“…[14] Syringocystadenocarcinoma papilliferum has been successfully treated with Moh's micrographic surgery. [15] To conclude, onset at puberty should alert one to the possibility of unusual location of SCAP. Solitary lesions in unusual locations generate multiple differential diagnoses and must be sent for histopathological examination.…”

Section: Discussion Discussionmentioning

confidence: 98%

Syringocystadenoma papilliferum on the thigh: An unusual location

Malhotra¹,

Singh²,

Ramesh³

2009

Indian J Dermatol Venereol Leprol

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A 28-year-old man presented with a partially eroded growth on the back of his right thigh for the last 15 years. Tuberculosis verrucosa cutis and pyogenic granuloma were suspected on clinical examination. Histopathological examination revealed syringocystadenoma papilliferum (SCAP). SCAP is rare on the thigh and a review of the English literature revealed eight cases. Non-descript clinical presentation in an unusual location and the rare linear and segmental variants lead to misdiagnosis. Onset at puberty should alert one to the possibility of the unusual location of SCAP.

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