Syphilitic uveitis in patients infected with human immunodeficiency virus

Tran, Thi Ha Chau; Cassoux, Nathalie; Bodaghi, Bahram; Fardeau, Christine; Caumes, Éric; LeHoang, Phuc

doi:10.1007/s00417-005-1137-6

Cited by 97 publications

(75 citation statements)

References 37 publications

(73 reference statements)

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“…Although initially thought to be specific of ocular syphilis in immunocompromised individuals (4)(5)(6) , ASPPC has been described in HIV negative patients without any evidence of immunocompromise as well (1,7) . In accordance with other studies, fluorescein angiogram showed irregular initial hyperfluorescence with hypofluorescent spots and late staining of the lesion (3,5,7) .…”

Section: Discussionmentioning

confidence: 99%

Optical coherence tomography and indocyanine green angiography findings in acute syphilitic posterior placoid choroidopathy: case report

Meira-Freitas¹,

Farah²,

Höfling-Lima³

et al. 2009

Arq. Bras. Oftalmol.

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Section: Discussionmentioning

confidence: 99%

Optical coherence tomography and indocyanine green angiography findings in acute syphilitic posterior placoid choroidopathy: case report

Meira-Freitas¹,

Farah²,

Höfling-Lima³

et al. 2009

Arq. Bras. Oftalmol.

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“…PCR analysis of ocular fluid samples may expedite the diagnosis and treatment of such conditions, which is important as the retinitis can progress rapidly. 11,15,16,42,43 Syphilis, once the main cause of vitreous opacities, 1 accounts for only about 1% of all vitreous opacities but is increasing in incidence, particularly in the HIV-positive population, 44 and should always be considered in the differential diagnosis of an inflammatory cellular vitreous infiltrate.…”

Section: Inflammatory Non-infectious Vitritismentioning

confidence: 99%

The pathologist's perspective on vitreous opacities

Coupland

2008

Eye

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“…62 Several studies, primarily from tertiary referral centers, have suggested a prevalence of ocular syphilis as high as 10% of HIV-infected patients who present with syphilis and ocular symptoms. [63][64][65] Given this unexpectedly high prevalence, ocular syphilis should be considered in any HIV-infected patient who presents with visual symptoms, irrespective of the patient's CD4 T-cell count. Every patient with syphilis and visual symptoms should be referred to the ophthalmologist for a formal evaluation for ocular disease.…”

Section: Neurosyphilismentioning

confidence: 99%

Syphilis in the United States: An Update for Clinicians With an Emphasis on HIV Coinfection

Zetola

Engelman

Jensen

et al. 2007

Mayo Clinic Proceedings

112

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Diagnosis and treatment of syphilis are challenging because of its variable clinical presentation and course and the lack of definitive tests of cure after treatment. This review of the most recent literature on the epidemiology, clinical manifestations, current diagnosis, and treatment of syphilis is focused toward clinicians who treat patients with this disease. Syphilis coinfection with human immunodeficiency virus is emphasized because it is increasingly common in the United States and affects the initial presentation, disease course, diagnosis, and treatment of syphilis. Of particular consequence is the effect of human immunodeficiency virus on the clinical diagnosis, prevalence, and course of neurosyphilis, one of the most serious consequences of syphilis infection. linicians from large metropolitan areas frequently face the challenge of diagnosing syphilis and treating patients with syphilis. In doing so, they are often faced with questions regarding interpretation of clinical findings and laboratory results and selection of appropriate therapy. Interpretation of the data available to answer these questions is often challenging given the paucity of large well-designed studies and the substantial variability that characterizes the clinical presentation of syphilis. Such a challenge is particularly found in the treatment of patients coinfected with syphilis and human immunodeficiency virus (HIV). To guide clinicians in this difficult task, we discuss the most recent literature on the epidemiology, clinical manifestations, diagnosis, and treatment of syphilis and the corresponding effects of HIV coinfection.

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Syphilitic uveitis in patients infected with human immunodeficiency virus

Cited by 97 publications

References 37 publications

Optical coherence tomography and indocyanine green angiography findings in acute syphilitic posterior placoid choroidopathy: case report

Optical coherence tomography and indocyanine green angiography findings in acute syphilitic posterior placoid choroidopathy: case report

The pathologist's perspective on vitreous opacities

Syphilis in the United States: An Update for Clinicians With an Emphasis on HIV Coinfection

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