Syphilitic Aortic Aneurysm in the Third Millennium

Re, Federico Del; Falcetta, Giosuè; Pratali, Stefano; Belgio, B.; Pucci, Angela; Bortolotti, Uberto

doi:10.1055/s-0039-1683399

Cited by 3 publications

(1 citation statement)

References 7 publications

(9 reference statements)

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“…Since ascending and thoracic aorta are rich in lymphatics, spirochetes have tropism for these aortic segments. [10][11][12][13] The tendency of spirochetes to dwell in the small vessels of the vasa vasorum leads to an adventitial chronic inflammation, mainly in the arterioles that perfuse the media layer. 6 The immune system response involves infiltration of plasmacytes and lymphocytes into the aortic wall layers, creating a diffuse and fibrous thickening of the intima.…”

Section: Discussionmentioning

confidence: 99%

Contained rupture of an aortic arch aneurysm in a patient with syphilitic aortitis. A case report

Bilman¹,

Bertoglio²,

Melissano³

et al. 2021

J. vasc. bras.

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Syphilitic aortitis is a rare complication of tertiary syphilis, which can lead to aortic aneurysm formation, aortic valvular insufficiency, and ostial coronary stenosis. Syphilis has re-emerged worldwide over recent decades and vascular surgeons should be aware of its cardiovascular manifestations. Atypical clinical presentation, such as hemoptysis and a computed tomography angiography pattern of a thicker aneurysmal wall with ulcer-like aneurysm projections, should raise suspicion of syphilitic aortic aneurysm. An early diagnosis and appropriate surgical and medical therapies significantly contribute to successful treatment and favorable prognosis. Herein is reported the case of an 82-year-old male patient, positive for syphilis infection, with impending aortic arch aneurysm rupture treated with a hybrid arch repair. After 7 months, the patient was brought to the emergency room in cardiac arrest. Unsuccessful cardiopulmonary resuscitation maneuvers were performed, and an autopsy showed cardiac tamponade due to rupture of the ascending aorta.

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Section: Discussionmentioning

confidence: 99%

Contained rupture of an aortic arch aneurysm in a patient with syphilitic aortitis. A case report

Bilman¹,

Bertoglio²,

Melissano³

et al. 2021

J. vasc. bras.

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The comeback of syphilitic aortitis

Martino

Bortolotti

Pucci³

2020

Cardiovascular Pathology

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Infecções em vasculites sistêmicas

Souza

2019

Rev Paul Reumatol

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Agentes infecciosos têm papel relevante na patogênese de vasculites sistêmicas “primárias” e podem funcionar como gatilhos para recidivas de doença. Porém, em algumas situações, como na poliarterite nodosa e na vasculite crioglobulinêmica, agentes infecciosos são agentes etiológicos que participam diretamente no desenvolvimento da vasculite e requerem tratamento específico para que o processo vasculítico seja completamente controlado. Agentes infecciosos também podem invadir diretamente a parede do vaso sanguíneo e levar a alterações arteriais que simulam vasculites primárias. Neste artigo, revisaremos as principais formas de vasculites associadas a agentes infecciosos e aquelas causadas diretamente pela invasão da parede do vaso por patógenos. Unitermos: Infecção. Vasculites sistêmicas. Vasculite crioglobulinêmica. Poliarterite nodosa. Vasculite cutânea. Vírus da hepatite C. Vírus da hepatite B. Vírus da imunodeficiência humana.

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Syphilitic Aortic Aneurysm in the Third Millennium

Cited by 3 publications

References 7 publications

Contained rupture of an aortic arch aneurysm in a patient with syphilitic aortitis. A case report

Contained rupture of an aortic arch aneurysm in a patient with syphilitic aortitis. A case report

The comeback of syphilitic aortitis

Infecções em vasculites sistêmicas

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