Syphilitic aneurysm of the ascending aorta

Paulo, Nelson; Cascarejo, José; Vouga, Luís

doi:10.1093/icvts/ivr067

Cited by 43 publications

(38 citation statements)

References 9 publications

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“…During the prepenicillin era, syphilis was a common cause of aortitis, 1,11,57 although by the 1950s its occurrence had markedly declined. 57 A report in 1958 on the relative occurrence of atherosclerotic and syphilitic thoracic aortic aneurysms showed cases of syphilis outnumbering atherosclerosis by a ratio of 1.3:1.…”

Section: Syphilitic Aortitismentioning

confidence: 99%

“…57 A report in 1958 on the relative occurrence of atherosclerotic and syphilitic thoracic aortic aneurysms showed cases of syphilis outnumbering atherosclerosis by a ratio of 1.3:1. 1 The pathologic process in syphilitic aortitis is almost always in the thoracic aorta, 1,12,57 in contrast to the distribution of atherosclerosis, which is more prevalent in the abdominal aorta (Table 2-2). 1 The pathologic process in syphilitic aortitis is almost always in the thoracic aorta, 1,12,57 in contrast to the distribution of atherosclerosis, which is more prevalent in the abdominal aorta (Table 2-2).…”

Section: Syphilitic Aortitismentioning

confidence: 99%

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Neurologic Complications of Aortic Disease and Surgery

Goodin¹

2014

Aminoff's Neurology and General Medicine

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Section: Syphilitic Aortitismentioning

confidence: 99%

Section: Syphilitic Aortitismentioning

confidence: 99%

Neurologic Complications of Aortic Disease and Surgery

Goodin¹

2014

Aminoff's Neurology and General Medicine

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“…Syphilitic aortic aneurysm is a rare occurrence in the antibiotic era, making the diagnostic assumption even more challenging (Paulo, Cascarejo, & Vouga, ). The vasa vasorum undergoes a process of endarteritis obliterans, necrosis of the medial layer (mesoarteritis), and infiltration of plasma cells.…”

Section: Introductionmentioning

confidence: 99%

Acute coronary syndrome of very unusual etiology

Barbosa‐Barros

Pérez‐Riera

Koivula

et al. 2018

Noninvasive Electrocardiol

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Aortitis is one of many possible manifestations of tertiary syphilis. Aortic disease is the most common of all cardiovascular syphilitic lesions. Aortic diseases caused by tertiary syphilis include aortitis, aortic root dilation, aneurysm formation, aortic regurgitation and coronary ostial stenosis. A less common manifestation of syphilitic aortitis is coronary artery ostial narrowing related to aortic wall thickening. We report a case of a 40-year-old male patient admitted with a clinical picture of acute coronary syndrome (unstable angina). He had no risk factors for coronary artery disease. The physical examination revealed nothing remarkable. The admission electrocardiogram (ECG) showed ST segment depression in the anterolateral and inferior leads (Figure 1). The coronary angiogram showed critical ostial stenosis of the right (RCA) and left main coronary artery (Figure 2a, b). Cardiac-computed tomography showed aortic wall thickening with involvement of bilateral coronary ostia (Figure 2b, c). The patient was referred for coronary bypass surgery after treatment with two doses of penicillin G. The laboratory test was strongly positive for syphilitic infection. Postoperative treatment with benzathine penicillin, in doses recommended for tertiary syphilis, was implemented.

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“…Late latent syphilis is the asymptomatic period after 1 year and can last from months to years . Lastly, tertiary syphilis is the late symptomatic period, and it can involve the skin, bones, soft tissues, the nervous and cardiovascular system, with findings such as: destructive syphilitic gummas, hemiparesis, aphasia, seizures, aortitis, aortic aneurysms, myocardial infarction and congestive heart failure …”

Section: Introductionmentioning

confidence: 99%

Late latent mucinous syphilis mimicking connective tissue disease

Gottesman

Schoenling²,

Culpepper

2017

J Cutan Pathol

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As evidenced by the Centers for Disease Control and Prevention (CDC) statistics, syphilis is yet again on the rise. It is known as the great mimicker because of its variable symptoms and how frequently it can be confused with other diseases. The different stages of syphilis (primary, secondary, latent, late latent and tertiary) are discussed. We describe a new histopathologic pattern of syphilis, one that mimics connective tissue disease and can represent a diagnostic pitfall. In this time and age, when syphilis is rising especially among the men who have sex with men subgroup, it is important to keep a high index of suspicion of syphilis even when clinically and histopathologically the findings on first glance may not appear characteristic.

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Syphilitic aneurysm of the ascending aorta

Cited by 43 publications

References 9 publications

Neurologic Complications of Aortic Disease and Surgery

Neurologic Complications of Aortic Disease and Surgery

Acute coronary syndrome of very unusual etiology

Late latent mucinous syphilis mimicking connective tissue disease

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