Proper positioning of premature babies resulting from different maternal chronic conditions before pregnancy and hypertension induced during pregnancy can promote normal balanced development with maximizing the sleeping conditions and minimizing the gastric reflux. We conducted a retrospective study on data from Bega Clinics - Obstetrics and Gynecology and Neonatology for 2012-2013 about premature babies of mothers with pathologic pregnancies. Part of the newborns was positioned in a flexible polyurethane foam cocoon and clinical observations on sleeping states and the presence of gastric reflux were noted. In our study, 453 (10.5%) cases of women with different pathological conditions out of 4,312 cases were encountered. Most of them (48%) had a diagnosis of chronic hypertension, followed by chronic renal diseases (34%). Hypertension developed during pregnancy for both years, happened in 340 (7.88%) cases. Severe forms of hypertension were noted in 57.05% of them. Incidence of preterm birth babies was 11.22% (484 cases), of which 12 cases (8.67%) resulted from pregnancies with different forms of hypertension. Clinical observations stated that sleeping quietly and awake and quiet have increased the most when compared with babies positioned in the cocoon (44 babies) compared with babies (45) out of cocoons. Only 8 (18.2%) babies positioned in the cocoon experienced gastric reflux comparatively with 41 babies that were positioned in regular conditions.