Synthetic lipids as a biocide candidate for disinfection of ballast water

Biocides as Biomedicines against Foodborne Pathogenic Bacteria

“…Unfortunately, although this biocide has shown exceptional results in the control of other pathogens, it was also mentioned by the authors to exhibit toxic effects on eukaryotic cells, so its application should be limited. On contrary, a new biocide synthesized from soybean oil and designed to control harmful aquatic microorganisms [ 84 ] (named LGPcide) showed strong bactericidal efficiency against P. fluorescens and other marine microorganisms. The authors concluded that after 24 h, LGPcide reduced pathogen presence by 99.5 % and showed a low toxicity compared to other maritime industrial biocides such as menadione, zinc sulfate, diuron, and irgarol.…”

Synthesis of natural 1-O-alkylglycerols: a study on the chemoselective opening of the epoxide ring by onium quaternary salts (N and P) and ionic liquids

“…[14][15][16] There are reports of some preparation methods of 1-Oalkylglycerols in the literature using derivatives of glycerol as starting materials. 13,[17][18][19][20][21][22][23][24][25] Some studies mention the synthesis of compounds 1, 2, and 3 from solketal, the isopropylidene ketal of glycerol. [20][21][22] These 1-O-alkylglycerols can also be synthetically obtained from glycidol, an epoxide of chemical structure similar to that of epichlorohydrin with a hydroxyl group.…”

“…We also demonstrated that lyso-glycerophosphocholines prepared from soy lecithins display potential biocide activity on the treatment of ballast water. 24 Herein, we prepared 1-O-alkylglycerols 1, 2, and 3 found in the skin and liver of sharks, stingrays, and chimeras, marine animals that do not present biofouling. This characteristic suggests that these substances (1, 2, and 3) are potential candidates to be incorporated in anti-fouling paints as biocides, becoming a green chemistry option to control the process of biofouling that leads to enormous losses for sea transport.…”

“…13 It is possible to notice that epichlorohydrin, an organochlorine compound used in various industrial applications, has been gaining relevance in the synthesis of 1-O-alkylglycerols. 13,23,24 Epichlorohydrin is obtained from glycerol, which is itself a by-product of the biodiesel production (biomass fuel) and was used in this study as the starting material.…”

“…Within the perspective of waste recovery from the industries of refined soy oil and biodiesel produced in Brazil, we used, in a recent study, starting materials such as epichlorohydrin 13 and soy lecitins 24 for the synthesis of potential biocides. We also demonstrated that lyso-glycerophosphocholines prepared from soy lecithins display potential biocide activity on the treatment of ballast water.…”