2018
DOI: 10.1074/jbc.tm117.000368
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Synthetic biology strategies for improving microbial synthesis of “green” biopolymers

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Cited by 52 publications
(27 citation statements)
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“…On the other hand, this technology is also used to produce fertilizers, plant development treatments and pesticides, due to the use of enzymes and molecules produced exclusively to generate that benefit to agriculture. Also favoring the manufacturing processes of the food industry and food safety systems in the cultivation fields through various molecular techniques to treat diseases and produce biosensors for the detection of pathogens [89,90,91].…”
Section: Impact and Applications Of Synthetic Biology In The Food Indmentioning
confidence: 99%
“…On the other hand, this technology is also used to produce fertilizers, plant development treatments and pesticides, due to the use of enzymes and molecules produced exclusively to generate that benefit to agriculture. Also favoring the manufacturing processes of the food industry and food safety systems in the cultivation fields through various molecular techniques to treat diseases and produce biosensors for the detection of pathogens [89,90,91].…”
Section: Impact and Applications Of Synthetic Biology In The Food Indmentioning
confidence: 99%
“…At the same time, the metabolic engineer's mastery of simpler living systems could result in equally profound societal impacts. For example, engineering bacteria to convert municipal waste into biodegradable plastics via processes that can be cost‐effectively operated at multiple scales could have the impact of breaking our dependence on fossil fuel‐derived polyolefins . And of course, to a chemical engineer what can be more appealing than harnessing metabolic engineering to transform row crops into factories capable of producing all kinds of value‐added chemicals?…”
Section: Metabolic Engineeringmentioning
confidence: 99%
“…Two of the main medically and industrially relevant biopolymers worldwide are cellulose and alginate. The global market for these two polymers currently amounts to over USD 22 billion per year, with projections to reach USD 50 billion by 2025 (Anderson et al ., ). At present, plants and algae are almost exclusively the sole sources of commercially available cellulose and alginate, respectively (Hay et al ., ; Heinze, ; García and Prieto, ).…”
mentioning
confidence: 97%
“…The biosynthesis of polymers is energetically demanding for bacteria, and their production is frequently highly regulated, with many biosynthetic gene clusters being cryptic under standard culture conditions (Rehm, ; Hay et al ., ; Schmid et al ., ; Perez‐Mendoza and Sanjuan, ). As a result, future synthetic biology strategies will be focused not only on developing à‐la‐carte bacterial polymers with specific chemical and physical properties but also on the construction of bacterial strains with improved production yields (Anderson et al ., ). This issue has been addressed by Valentine and co‐workers in a recent report published in Microbial Biotechnology using Pseudomonas aeruginosa PAO1 as model bacterium (Valentine et al ., ).…”
mentioning
confidence: 97%