Synthesizing molecularly imprinted polymer beads for the purification of vitamin E

A molecularly imprinted polymer for the efficient adsorption of morphine

“…In comparison, the isotherm data on NIP MAA generated a single straight line only, which corresponds to the general affinity of the polymeric matrix. These observations are consistent with our previous studies with other MIPs 14,17 …”

“…The standard nitrogen isotherm was measured on MIP MAA and shown in Figure S1 in the Supporting Information, from which the BET surface area was calculated as ~49 m 2 /g and a pore volume of 0.23 cc/g. The MIP was found largely macroporous, consistent with our previous researches on similar MIP samples 14,17,23 …”

“…When the IP ratio is further increased to (1:2) on M4, the amount of functional monomers is relatively small, so that less binding sites were generated; When the IP ratio is lowered from 1:3 (M5) to 1:6 (M7), the molar ratio of functional monomers was gradually increased, so that more nonspecific sites were formed within the polymer matrix. Such nonspecific sites, which are similar to these of NIP, present weaker and nonspecific interaction with morphine molecules and subsequently result in decreased capacity and selectivity 14,17,25 . Therefore, the IP ratio of (1:3), which was also proposed by other studies, 10 was selected as the optimal ratio for the synthesis of MIP MAA .…”

“…After 5 adsorption–desorption cycles in the batch adsorber, the MIP was able to retain ~92% of its original adsorption capacity. The capacity loss may be due to the fact that the batch process, although more economical due to the less consumption of solvents, is less efficient than the fixed bed elution system used in our previous studies 21,17 …”

“…12 These sites (or cavities) are complementary to the geometry and surface chemistry of the template molecule so that they present good adsorption selectivity and capability in a complex solution of mixtures. [12][13][14] This technology has been quickly developed and widely used in sensing technologies 15,16 and separation applications of metal ions, 13 vitamins, 17 antibiotics, 14 proteins, 18,19 and chiral molecules, 20 etc.…”