Synthesized Mammography: Clinical Evidence, Appearance, and Implementation

Durand, Melissa A.

doi:10.3390/diagnostics8020022

Cited by 35 publications

(36 citation statements)

References 32 publications

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“…There are some artifacts that can jeopardize DBT image quality. The most frequent artifacts related to calcifications are shadowing and zipper artifacts (9,19,(45)(46)(47). Shadowing, also termed slinky artifact, corresponds to dark lines resembling shadows adjacent to large calcifications that are typically depicted on SM views, while zipper artifacts represent repetition of dense calcifications or metallic material out of plane on the DBT image stack (Fig 8).…”

Section: Calcification Artifacts At Dbtmentioning

confidence: 99%

Calcifications at Digital Breast Tomosynthesis: Imaging Features and Biopsy Techniques

et al. 2019

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Full-field digital mammography (FFDM), the standard of care for breast cancer screening, has some limitations. With the advent of digital breast tomosynthesis (DBT), improvements including decreased recall rates and increased cancer detection rates have been observed. The quasi-three-dimensional capability of DBT reduces breast tissue overlap, a significant limitation of FFDM. However, early studies demonstrate that a few cancers detected at FFDM may not be diagnosed at DBT-only screening, and lesions with calcifications as the dominant feature may look less suspicious at DBT or not be visible at all. These findings support the use of combined FFDM and DBT protocols to optimize screening performance. However, this combination would approximately double the patient's radiation exposure. The development of computer algorithms that generate two-dimensional synthesized mammography (SM) views from DBT has improved calcification conspicuity and sensitivity. Therefore, SM may substitute for FFDM in screening protocols, reducing radiation exposure. DBT plus SM demonstrates significantly better performance than that of FFDM alone, although there are reports of missed malignant calcifications. Thus, some centers continue to perform FFDM with DBT. Use of DBT in breast imaging has also necessitated the development of DBT-guided biopsy. DBT-guided biopsy may have a higher success rate than that of stereotactic biopsy, with a shorter procedure time. While DBT brings substantial improvements to breast cancer imaging, it is important to be aware of its strengths and limitations regarding detection of calcifications. This article reviews the imaging appearance of breast calcifications at DBT, discusses calcification biopsy techniques, and provides an overview of the current literature.

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Section: Calcification Artifacts At Dbtmentioning

confidence: 99%

Calcifications at Digital Breast Tomosynthesis: Imaging Features and Biopsy Techniques

et al. 2019

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“…In addition, long-term studies are beginning to reflect that the improvements seen with DBT are not bound to prevalent screening but persist on incident screening. All this has made DBT increasingly requisite at many institutions, both community and academic [6].…”

Section: Introductionmentioning

confidence: 99%

“…approval, multiple studies have evaluated the clinical performance of s2D. In clinical practice, s2D images are not identical to conventional 2D images and are designed for interpretation with DBT as a complement [6].…”

Section: Introductionmentioning

confidence: 99%

“…Furthermore, this precludes women with implants or large breasts requiring tiling, from receiving DBT, as their screening exams already include additional views. In addition, though the patient may remain in the same compression, the DBT and conventional 2D exams are acquired sequentially, with the addition of DBT adding 3.7-25 s onto the conventional 2D exam, depending on vendor [6].…”

Section: Introductionmentioning

confidence: 99%

“…To evaluate s2D+DBT as a valid clinical tool, the synthesized mammography literature is reviewed here and appraised in accordance with known screening criteria. Implementation suggestions and case examples are also provided herein to ease transition for radiologists considering s2D+DBT as a replacement for 2D+DBT [6].…”

Section: Introductionmentioning

confidence: 99%

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Study of role of digital breast tomosynthesis over digital mammography in the assessment of BIRADS 3 breast lesions

Ali

Adel

2019

Egypt J Radiol Nucl Med

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Background: Breast cancer is the most common malignancy in women and thus, screening has become an important health issue. Although mammography remains the standard of care for breast cancer screening and diagnosis (with biopsy), tomosynthesis (3D DBT) allows the separation of overlapping structures seen on 2D mammography and thus enables better depiction of masses or asymmetries. Results: A prospective study for mammographic cases referred to our radiology unit included 60 lesions detected in 59 patients that were performed during the period from January 2016 to September 2017. Patients' ages ranged from 26 to 72 years with mean age 51 ± 12 SD. Sixty percent of breast imaging-reporting and data system (BIRADS) 3 lesions detected by 2D digital mammography (36/60) changed their category after 3D DBT, 40% (24/60) digital mammography noticed lesions did not change their BIRADS after 3D DBT. Twenty-nine BIRADS 3 lesions out of the 60 were downgraded to BIRADS 1and 2, while 7 BIRADS 3 lesions out of the 60 were upgraded to BIRADS 4 and 5 which were all biopsied. Six out of the 7 lesions were pathologically proven ducal carcinoma and 1 out of 7 pathologically proven to be atypical ductal hyperplasia. Conclusion: 3D DBT significantly reduced the need for additional mammographic views and frequent follow-up studies as it gave better characterization for all BIRADS 3 lesions.

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On Digital Breast Tomosynthesis and Mammography with Contrast Medium: Notes on Molecular Breast Imaging

Poggi

2024

Breast Imaging Techniques for Radiographers

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Synthesized Mammography: Clinical Evidence, Appearance, and Implementation

Cited by 35 publications

References 32 publications

Calcifications at Digital Breast Tomosynthesis: Imaging Features and Biopsy Techniques

Calcifications at Digital Breast Tomosynthesis: Imaging Features and Biopsy Techniques

Study of role of digital breast tomosynthesis over digital mammography in the assessment of BIRADS 3 breast lesions

On Digital Breast Tomosynthesis and Mammography with Contrast Medium: Notes on Molecular Breast Imaging

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