Synthesis, Thermal Behavior, and Antimicrobial Activity of Polyether Based on 4,7-dichloro 6-nitroquinazoline

Simple and efficient synthesis with theoretical calculations of novel N-halamine monomers

“…During the past decade, the great interest has been devoted to biocidal polymers, which are able to kill pathogenic microorganisms or at least are characterized by the high resistance to microbial attack. [1][2][3][4][5][6][7][8][9][10] Polystyrene, is the thermoplastic material applied in numerous industrial branches, and its properties are well known since many years and are often modified for manufacturing the modern plastics with completely different properties than origin polymer. [11][12][13][14] On the other hand, hydantoins represent a group of compounds which over the past few years has also attracted great attention because of their diverse biological activities including antibacterial, antiviral, fungicidal, herbicidal, analgesic, antiarythmic, antihypertensive, antidiabetic, HDL/cholesterol modulating, anticonvulsant, and cancer chemotherapeutic activity.…”