Synthesis, Structure and Biological Activities of Some Novel Anthranilic Acid Esters Containing N‐Pyridylpyrazole

Abstract

In search of environmentally benign insecticides with high activity, low toxicity and low residue, a novel series of anthranilic acid esters containing N‐pyridylpyrazole were designed and synthesized. All of the compounds were characterized and confirmed by IR, 1H NMR, MS and elemental analysis. The single crystal structure of 14d was determined by X‐ray diffraction. The bioassay tests showed that the synthesized compounds exhibited good insecticidal activities against Mythimna separata Walker and Culex pipiens pallens.

Synthesis, insecticidal activities and SAR of novel phthalamides targeting calcium channel

“…33 The insecticidal activity against oriental armyworms was tested by foliar application; individual corn (Tangyu 10, Zeamays L.) leaves were placed on moistened pieces of filter paper in Petri dishes. The leaves were then sprayed with the test solution and allowed to dry.…”

Design, Synthesis and Insecticidal Evaluation of Novel Pyrazolecarboxamides Containing Cyano Substituted N‐Pyridylpyrazole

“…All solvents and liquid reagent were dried Scheme 1 General synthetic procedure of compounds 6a-6m by standard methods in advance and distilled before use. Chlorantraniliprole was synthesized according to the literature 8 and used as the control.…”

“…7 2-Amino-5-chloro-N,3-dimethylbenzamide (5m) was synthesized by the method reported by Dong et al 8 The title compounds were prepared as shown in Scheme 1.…”

“…8 The insecticidal activity against oriental armyworm was tested by foliar application, individual corn leaves were placed on moistened pieces of filter paper in Petri dishes. The leaves were then sprayed with the test solution and allowed to dry.…”

Synthesis and Anti-Microbial Activities of 1,3,5-Trisubstituted-Pyrazole Derivatives Containing a Pyridyl Moiety

“…In addition, the pyridyl ring is also a prominent heterocyclic scaffold in lot of bioactive molecules. Many pyridine-based compounds have been reported to exhibit versatile bioactivities, such as insecticidal, fungicidal, anticancer and antibacterial activities [11][12][13]. Keeping this in view, we choose the pyridyl ring as one of the aryl substituents about the central pyrazole ring to synthesize a series of new 1,3,5-trisubstituted-pyrazole derivatives containing a pyridyl moiety.…”