Synthesis, Structural Characterization and Biological Activity of Cu(II) Compounds Incorporating Pyrazole‐derived Ligand: Effect on Cell Growth in Human Colorectal Carcinoma
Abstract:A series of Cu(II) compounds containing neutral multi‐dentate ligand [2,6‐diisopropylphenyl]‐bis[(1‐H‐pyrazol‐1‐yl)methyl]amine (L1) and pyrazole dimethoxethyl ligand [(1‐H‐pyrazol‐1‐yl)methyl]‐bis(2‐methoxyethyl)amine (L2) were synthesized. Reactions of L1 and L2 with copper(II) chloride generate L1CuCl2 (1) and L2CuCl2 (2), respectively. Compounds 1 and 2 have been characterized by elemental analysis and X‐ray single crystal diffractometry. The effects of compounds 1 and 2 on the cell viability of various hu… Show more
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