Synthesis, structural characterization, and antimicrobial evaluation of new mononuclear mixed ligand complexes based on furfural-type imine ligand, and 2,2′-bipyridine

Abstract

The present investigation goal was to investigate the chemistry of four new mononuclear mixed ligand Fe(III), Co(II), Cu(II), and Cd(II) complexes constructed from furfural-type imine ligand (L), and the co ligand 2,2′-bipyridine in addition to assessing their antimicrobial activity against some bacterial, and fungi strains. The structure of the complexes was interpreted by different spectroscopic techniques such as MS, IR, 1H NMR, UV–Vis, elemental analysis, TG-DTG, conductivity, and magnetic susceptibility measurements. The correlation of all results revealed that ligand (L) acts as a neutral ONNO tetradentate whereas the co ligand acts as a neutral NN bidentate. The coordination of the ligands with the metal ions in a molar ratio of 1:1:1 leads to formation of an octahedral geometry around the metal ions. The octahedral geometry has been validated and optimized by DFT analysis. Conductivity data showed the electrolytic nature of all complexes. The thermal stability of all complexes was deduced in addition to evaluating some thermodynamic, and kinetic parameters using Coats–Redfern method. Furthermore, all complexes in comparison to their parent ligands were tested for their biological potency against some pathogenic bacterial, and fungi strains using the paper disk diffusion method. [CdL(bpy)](NO3)2 complex revealed the highest antimicrobial activity.

Manipulation of Bowl-Shaped Nanoparticles Self-Assembled from a Bipyridine Pendant Containing Homopolymer

“…Therefore, we explored the effect of the species and the feeding ratio of various metal ions on the self-assembly behavior of PBPyAA. First, Co 2+ was selected as model divalent ions . When the molar ratio of BPy to Co 2+ was 27:1, the D h of the assemblies decreased from 805 to 559 nm while the zeta potential increased from −31.9 to +13.7 mV (Figure S23), which implied that the coordination of Co 2+ increased the hydrophilicity of the PBPyAA and promoted the migration of Co 2+ coordinated BPy to the surface.…”

Metal–ligand synergy driven functionalisation of alkylene linked bis(aldimine) on a diruthenium(ii) platform. Cyclisation versus oxygenation

“…Bis(aldimine) based ligands and their metal complexes play a prominent role in catalytic 7 and biological processes. 8 A few important reactivity aspects of aldimines include the attack of nucleophiles, alkyl/aryl transfer, insertion of carbene or nitrene and oxygenation via the activation of O 2 . 9 In this regard, our recent work highlights C–C coupling of the ethylene linked bis(aldimine) core of L1 ( syn -(CH 2 ) 2 ) on the electron-rich {Ru II (acac) 2 } (acac = acetylacetonate) platform in 1 to generate pyrazine (L1′) bridged 1a , whereas the same L1 in the corresponding 2 ( anti -(CH 2 ) 2 ) remains unaltered under a N 2 atmosphere (Scheme 1).…”