Synthesis, spectroscopic characterization, electrochemistry and biological evaluation of some binuclear transition metal complexes of bicompartmental ONO donor ligands containing benzo[b]thiophene moiety

Synthesis, characterization and biological relevance of some metal (II) complexes with oxygen, nitrogen and oxygen (ONO) donor Schiff base ligand derived from thiazole and 2-hydroxy-1-naphthaldehyde

“…Recently we have reported the synthesis, characterization and biological activities of some metal (II) complexes of Schiff bases containing thiazole, benzo [b]thiophene and quinoline moieties [17][18][19]. Exhilarated by these reports, we have synthesized the novel Schiff base ligand 2-((2-hydroxynaphthalen-1-yl) methylene)-N-(4-phenylthiazol-2-yl) hydrazinecarboxamide (L) containing carbonyl, azomethines and hydroxyl groups as potential chelating sites.…”

Crystal structure of 2-(4-methyl-3-phenylthiazol-2(3H)-ylidene)malononitrile, C13H9N3S

“…A literature survey revealed that thiophene, pyrazole, arylhydrazone, and 2-pyridone derivatives are important scaffolds in pharmacologically active compounds. Regarding thiophene ligands, their metal complexes possess antimicrobial activities [7]. Cyanothiophene scaffolds act as MurF ligase inhibitor, which prevents the bacterial peptidoglycan biosynthesis [8].…”

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“…Mass spectrum was recorded using Bruker microtop-QII. 1 H NMR spectra were recorded on Bruker Advanced DPX-300 spectrometer using DMSO-d 6 as a solvent and TMS as an internal solvent. Electronic spectral studies were conducted on a perkin elmer-lambda 25, UV spectrophotometer.…”