Synthesis, spectroscopic characterization, and crystal structures of two chlorodiorganotin(IV) 4-(2-methoxyphenyl)piperazine-1-carbodithioates

Rehman, Zia ur; Barsan, Mirela M.; Wharf, Ivor; Muhammad, Niaz; Ali, Saqib; Meetsma, Auke; Butler, Ian S.

doi:10.1016/j.ica.2008.05.006

Cited by 28 publications

(4 citation statements)

References 15 publications

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“…As a result of “L” being a chelating ligand with a small bite forming a four‐membered ring, the S(1)–Sn–S (2) angle is not 90°, but only 63.12°. Therefore, the S(2) atom cannot occupy exactly the trans axial position to C (17) and C (17)–Sn–S (2) angle is 154.41°, closely related to the value (156.63 (4)) found in Ph 3 SnS 2 CN(C 5 H 11 ) . The Sn–C bond length, Sn(1)–C(17) (2.165 Å) (ax) , is very similar to equatorial ones, Sn(1)–C(11) (2.140 A°) (eq) and Sn(1)–C(23) 2.150 Å.…”

Section: Resultsmentioning

confidence: 55%

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New Supramolecular Triorganotin(IV) Dithiocarboxylates as Potential Antibacterial Agents

Rehman

Muhammad

Shah

et al. 2012

Heteroatom Chemistry

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Four triorganotin derivatives of general formula C10H10NS2SnR3,, where R = CH3 (1), C4H9 (2), C6H11 (3), and C6H5 (4), have been synthesized by the metathesis reaction of 1,2,3,4‐tetrahydroisoquinolnium salt of ligand with triorganotin(IV) chloride in the 1:1 ratio. These complexes were characterized by elemental analysis, Raman, IR, multinuclear NMR (1H, 13C, and 119Sn), and mass spectrometry. The crystal structure confirmed a supramolecular zig‐zag chain structure mediated by S–H (2.968 Å) for complex 4 with the central Sn atom exists in a distorted trigonal bipyramidal geometry. A subsequent antibacterial study indicates that the compounds are biologically active.

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Section: Resultsmentioning

confidence: 55%

“…The Sn–C bond length, Sn(1)–C(17) (2.165 Å) (ax) , is very similar to equatorial ones, Sn(1)–C(11) (2.140 A°) (eq) and Sn(1)–C(23) 2.150 Å. Finally, the S–C bond lengths are intermediate between the values expected for single and double bonds and are characteristic of the dithiocarboxylate group . The packing diagram of 4 (Fig.…”

Section: Resultsmentioning

confidence: 77%

New Supramolecular Triorganotin(IV) Dithiocarboxylates as Potential Antibacterial Agents

Rehman

Muhammad

Shah

et al. 2012

Heteroatom Chemistry

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“…Spectroscopic data and the crystal structures for 9 and 10 have already been published by our group [24].…”

Section: Biocidal Activitiesmentioning

confidence: 99%

Supramolecular organotin(IV) dithiocarboxylates as potential antimicrobial agents

Rehman

Muhammady

Shah

et al. 2012

Journal of Coordination Chemistry

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A series of tri-, chlorodi-, and diorganotin(IV) derivatives of 4-(2-methoxyphenyl)piperazine-1-carbodithioate (L) {R ¼ n-C 4 H 9 (1), C 6 H 11 (2), CH 3 (3) and C 6 H 5 (4)}, (n-C 4 H 9 ) 2 SnClL (5) and R 2 SnL 2 {R ¼ n-C 4 H 9 (6), C 2 H 5 (7), CH 3 (8)} have been synthesized by refluxing organotin(IV) chlorides with the ligand-salt in the appropriate molar ratio. Elemental analysis, Raman, IR, multinuclear NMR ( 1 H, 13 C and 119 Sn), mass spectroscopic, and single-crystal X-ray crystallographic studies were undertaken to elucidate the structures of the new compounds both in solution and in the solid state. The X-ray diffraction work reveals supramolecular structures for 4 and 6, with distorted trigonal-bipyramidal and distorted octahedral geometries around Sn, respectively. The ligand and several of the new compounds are good antimicrobial agents.

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“…Hussain et al compounds with different carboxylic acids Hanif et al, 2007;Ahmed et al, 2007;Zia-ur-Rehman et al, 2008;Ahmad et al, 2008a, Ahmad et al, 2008b, in this article, we present a synthesis of some new organotin(IV) compounds. The structure of these compounds has been evaluated by mass spectrometry and X-ray analysis in solid-state and multinuclear ( 1 H, 13 C) nuclear magnetic resonance (NMR) in solution form.…”

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confidence: 93%

Structure elucidation and inhibitory effects of self-assembled organotin(IV) esters ofp-tolyl acetic acid on bacterial, fungal, brine shrimp, and potato tumor cells

Hussain¹,

Ahmad²,

Hanif³

et al. 2010

Drug and Chemical Toxicology

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Biologically active new organotin(IV) acetates (1-6) of p-tolyl acetic acid have been synthesized and characterized by multinuclear nuclear magnetic resonance ((1)H, (13)C) and mass spectrometry. The X-ray crystallographic data of compounds (3 and 4) were also collected. These studies show that in diorganotin(IV) compounds (compounds 1, 2, 3, and 6), tin exists in skew trapezoidal geometry with four strong and two weaker bonds, whereas triorganotin(IV) carboxylates (compounds 4 and 5) have four and five coordinated geometries in solution and solid form, respectively. These compounds were screened for a range of biological activities. Antibacterial activities were determined against six pathogenic bacterial strains, three Gram-positive and three Gram-negative; the activities were measured in terms of inhibition zones (mm). Antifungal activities were determined against six pathogenic fungal strains, cytotoxicity by the brine shrimp lethality assay, and antitumor activities by the crown gall tumor inhibition (potato disc) assay.

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Synthesis, spectroscopic characterization, and crystal structures of two chlorodiorganotin(IV) 4-(2-methoxyphenyl)piperazine-1-carbodithioates

Cited by 28 publications

References 15 publications

New Supramolecular Triorganotin(IV) Dithiocarboxylates as Potential Antibacterial Agents

New Supramolecular Triorganotin(IV) Dithiocarboxylates as Potential Antibacterial Agents

Supramolecular organotin(IV) dithiocarboxylates as potential antimicrobial agents

Structure elucidation and inhibitory effects of self-assembled organotin(IV) esters ofp-tolyl acetic acid on bacterial, fungal, brine shrimp, and potato tumor cells

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