Synthesis, spectroscopic characterization and catalytic activity of 1-(2-hydroxybenzylideneamino)-5-(4-methylbenzoyl)-4-(4-methylphenylpyrimidin)-2(1<i>H</i>)-one

Aslan, Güzin; Akkoç, Senem; Akkurt, Mehmet; Özdemir, Namık; Kökbudak, Zülbiye

doi:10.1080/22243682.2018.1442742

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General Procedures For the Synthesis1

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2021

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“…Compound S1 was prepared according to our previous study protocol (Aslan et al, 2018). 10 mL of ethyl alcohol was added to over 2.10 -4 mmoles of S1.…”

Section: General Procedures For the Synthesismentioning

confidence: 99%

Yeni Metal Komplekslerinin Sentezi ve Sitotoksik Aktivite Değerlendirmesi

Aslan¹,

Akkoç

Kökbudak

2021

Erzincan Üniversitesi Fen Bilimleri Enstitüsü Dergisi

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Salicylaldehyde and 1-amino-5-(4-methylbenzoyl)-4-p-tolylpyrimidin-2(1H)-one were used for preparing a Schiff base, which is 1-(2-hydroxybenzylideneamino)-5-(4-methylbenzoyl)-4-p-tolylpyrimidin-2(1H)-one (S1). Three new complexes (Ag(I), Pd(II), and Pt(II)) were synthesized from this chelate ligand (S1). The Ag(I) complex was screened against the human colon cancer cell line, and the silver complex was found to have more cytotoxic activity than a standard drug used.

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“…Compound S1 was prepared according to our previous study protocol (Aslan et al, 2018). 10 mL of ethyl alcohol was added to over 2.10 -4 mmoles of S1.…”

Section: General Procedures For the Synthesismentioning

confidence: 99%