Synthesis, spectroscopic characterization and biological evaluation of a novel chemosensor with different metal ions

Gaber, Mohamed; Fayed, Tarek A.; El‐Nahass, Marwa N.; Diab, H.A.; El‐Gamil, Mohammed M.

doi:10.1002/aoc.5133

Cited by 24 publications

(14 citation statements)

References 57 publications

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“…Molecular orbital coefficients α 2 (covalent in‐plane σ‐bonding) and β 2 (covalent in‐plane π‐bonding) were estimated using the following equations [ 22 ] :

α^{2} goodbreak= ((), A_{∥} ∕ 0.036) goodbreak+ ((), g_{∥} goodbreak- 2.0023) goodbreak+ ((), 3 ∕ 7) ((), g_{⊥} goodbreak- 2.0023) goodbreak+ 0.04,

β^{2} goodbreak= ((), g_{∥} goodbreak- 2.0023) E / goodbreak- 8 λ α^{2},

γ^{2} goodbreak= \frac{((), g_{⊥} goodbreak- 2.0023) E}{- 2 λ α^{2}},

where λ = −828 cm −1 for the free copper ion and E is the electronic transition energy. α 2 = 1 indicates complete ionic character, whereas α 2 = 0.5 means pure covalent bonding, with the hypothesis of negligibly small values of the overlap integral.…”

Section: Resultsmentioning

confidence: 99%

Synthesis, spectroscopic and thermal studies of Cu⁺², Ni⁺²and Co⁺³complexes of Schiff base containing furan moiety. Antitumor, antioxidant, antibacterial and DNA interaction studies

Venkateswarlu

Lakshmi

Shivaraj

2021

Applied Organom Chemis

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Three mononuclear bioefficient imine‐based coordination complexes [Cu(FMIMBCP)2] (1), [Ni(FMIMBCP)2] (2), and [Co(FMIMBCP)3] (3) were synthesized using ligand [FMIMBCP = (((furan‐2‐yl)methylimino)methyl)‐6‐bromo‐4‐chlorophenol]. The formation of the complexes was ascertained by elemental analysis, Fourier transform infrared, UV–Visible, electrospray‐mass spectrometry, electron paramagnetic resonance, and thermogravimetric analysis. From the thermogravimetric curves, the kinetic and thermodynamic parameters of the thermal degradation steps were computed. The stability of the complexes has been calculated from quantum chemical parameters using HOMO‐LUMO energies. The comparative binding propensity profiles of above synthesized complexes with the calf thymus‐DNA were investigated via UV absorption and fluorescence studies. On the basis of extended conjugation and increased chromophores, complex 3 exhibited superior bioactivity with greater calculated DNA binding constant values, (Kb) 5.73 × 104 M−1 (3) as compared to complexes 1 (2.96 × 104 M−1) and 2 (8.38 × 103 M−1). The competitive binding titration with ethidium bromide (EB) revealed that metal complexes efficiently displace EB from the EB‐DNA system. The complexes were found to have pronounced cleavage efficiency as evaluated from agarose gel electrophoresis. The anticancer activity of the ligand and metal complexes against MCF‐7 and KB3 cells revealed that the complexes were more efficacious than the corresponding ligand. Further, in vitro antioxidant activity against DPPH proclaimed the remarkable bioefficiency of compounds, which makes them promising as an active chemotherapeutic agent. The complexes have strong antibacterial activity against Bacillus thuringiensis, Streptococcus pneumoniae, Escherichia coli, and Pseudomonas putida.

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“…Molecular orbital coefficients α 2 (covalent in‐plane σ‐bonding) and β 2 (covalent in‐plane π‐bonding) were estimated using the following equations [ 22 ] :

α^{2} goodbreak= ((), A_{∥} ∕ 0.036) goodbreak+ ((), g_{∥} goodbreak- 2.0023) goodbreak+ ((), 3 ∕ 7) ((), g_{⊥} goodbreak- 2.0023) goodbreak+ 0.04,

β^{2} goodbreak= ((), g_{∥} goodbreak- 2.0023) E / goodbreak- 8 λ α^{2},

γ^{2} goodbreak= \frac{((), g_{⊥} goodbreak- 2.0023) E}{- 2 λ α^{2}},

Section: Resultsmentioning

confidence: 99%

Synthesis, spectroscopic and thermal studies of Cu⁺², Ni⁺²and Co⁺³complexes of Schiff base containing furan moiety. Antitumor, antioxidant, antibacterial and DNA interaction studies

Venkateswarlu

Lakshmi

Shivaraj

2021

Applied Organom Chemis

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“…These results indicated the presence of organic molecules which supports in reducing particles growth of CdO NPs and resulted in smaller particle size (Madhumitha, Elango, & Roopan, 2016). The use of P. oxalicum cultural filtrate provided organic surface to synthesized NPs, which would enhance bactericidal effect of CdO NPs (Gaber, Fayed, El‐Nahass, Diab, & El‐Gamil, 2019).…”

Section: Resultsmentioning

confidence: 99%

Synthesis and characterization of microbial mediated cadmium oxide nanoparticles

Asghar

Habib

Zaman

et al. 2020

Microscopy Res & Technique

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Microbial mediated synthesis of metallic nanoparticles constitutes as effective and promising approach for the development of antibacterial materials in the field of bioengineering and biomedicine. We prepared Cadmium oxide nanoaprticles (CdO NPs) utilizing Penicillium oxalicum, and cadmium acetate solution via coprecipitate method. The elemental composition and morphology of these synthesized CdO NPs were examined through X-ray diffraction (XRD), UV-Vis absorption spectroscopy, Fourier transform infrared spectroscopy (FTIR), Scanning electron microscopy (SEM), and Energy dispersive spectroscopy (EDS). Furthermore, we evaluated the bactericidal potential of prepared CdO NPs using Escherichia coli (E.coli), Staphylococcus aureus (S.aureus), Bacillus cereus (B.cereus), and Pseudomonas aeruginosa (P. aeruginosa). Dimethyl sulfoxide was used as negative control while erythromycin was used as positive control. The XRD spectrum revealed cubic crystalline nanoparticles with 22.94 nm size and UV showed absorbance peak at 297 nm with 2.5 eV band gap energy. FTIR depicted O─H and carboxylic groups along with CdO stretching vibration. EDS showed the presence of organic compounds on Cd and O over NPs surface. SEM results revealed the spherical shape of the CdO NPs. The synthesized NPs exhibited highly potent bactericidal activity against selected strains and demonstrated less optical density of 0.086 after 24 hr. Owing to the significant antibacterial activity of CdO NPs, the broad application prospects of these nanoparticles CdO NPs in extensive biomedical applications is indicated.

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“…This is due to increasing the values of T Δ S * significantly from one step to another which overrides the values of Δ H *. [ 52 ] The negative Δ S * values for the decomposition steps indicate that all studied complexes are more ordered than the reactant. [ 53 ] The positive values of Δ H * mean that the decomposition processes are endothermic.…”

Section: Resultsmentioning

confidence: 99%

Cu (II), Zn (II), and Ce (III) metal complexes as antimicrobial pigments for surface coating and flexographic ink

Elsawy

Faheim

Salem

et al. 2021

Applied Organom Chemis

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Metal complexes, which were prepared from the reaction of an N‐salicylidene(4‐aminotoluene‐3‐sulfonic acid) Schiff base ligand (H2L) with Cu (II), Zn (II), and Ce (III), were characterized and confirmed by elemental analysis, molar conductance measurement, melting point, Fourier transform infrared (FT‐IR) spectroscopy, proton nuclear magnetic resonance (1H NMR), electronic spectra, magnetic susceptibility, thermal analysis, and qualitative and quantitative antimicrobial studies. The geometry of the compounds was optimized using the semiempirical PM3 Hamiltonian with Restricted Hartree–Fock (RHF) and root‐mean‐square (RMS) gradient of 0.05 kcal/mol. The ligand and its metal complexes were physically incorporated into a water‐based paint and flexographic ink formulation to study their antimicrobial properties and performances as metal‐complex pigments. The results of their performance tests further enhanced their applications as pigments. The mechanical resistance of the prepared paint and ink was also studied to evaluate the possible drawbacks that were associated with the addition of the prepared pigments. Compared with the blank sample, the studies indicated that the physical incorporation of Cu complexes slightly enhanced the mechanical properties of the painted films (the gloss values, hardness, and adhesion) and printed paper (gloss, color strength [density], and abrasion resistance) according to the American Society for Testing and Materials (ASTM). Further, regarding the antimicrobial test, the obtained results can be represented according to the following activity order: the prepared ligand > Zn complex > Ce complex > Cu complex before or after the incorporations of the paint and ink.

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Synthesis, spectroscopic characterization and biological evaluation of a novel chemosensor with different metal ions

Cited by 24 publications

References 57 publications

Synthesis, spectroscopic and thermal studies of Cu⁺², Ni⁺²and Co⁺³complexes of Schiff base containing furan moiety. Antitumor, antioxidant, antibacterial and DNA interaction studies

Synthesis, spectroscopic and thermal studies of Cu⁺², Ni⁺²and Co⁺³complexes of Schiff base containing furan moiety. Antitumor, antioxidant, antibacterial and DNA interaction studies

Synthesis and characterization of microbial mediated cadmium oxide nanoparticles

Cu (II), Zn (II), and Ce (III) metal complexes as antimicrobial pigments for surface coating and flexographic ink

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Synthesis, spectroscopic characterization and biological evaluation of a novel chemosensor with different metal ions

Cited by 24 publications

References 57 publications

Synthesis, spectroscopic and thermal studies of Cu+2, Ni+2and Co+3complexes of Schiff base containing furan moiety. Antitumor, antioxidant, antibacterial and DNA interaction studies

Synthesis, spectroscopic and thermal studies of Cu+2, Ni+2and Co+3complexes of Schiff base containing furan moiety. Antitumor, antioxidant, antibacterial and DNA interaction studies

Synthesis and characterization of microbial mediated cadmium oxide nanoparticles

Cu (II), Zn (II), and Ce (III) metal complexes as antimicrobial pigments for surface coating and flexographic ink

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Synthesis, spectroscopic and thermal studies of Cu⁺², Ni⁺²and Co⁺³complexes of Schiff base containing furan moiety. Antitumor, antioxidant, antibacterial and DNA interaction studies

Synthesis, spectroscopic and thermal studies of Cu⁺², Ni⁺²and Co⁺³complexes of Schiff base containing furan moiety. Antitumor, antioxidant, antibacterial and DNA interaction studies