Synthesis, spectroscopic characterization and antimicrobial studies of mercury(II) complexes of thiolates

Abstract

Abstract. Mercury(II) complexes of thiolates having the general formula [Hg(RS)Cl 2 ]− and [Hg(RS) 2 ] have been prepared and characterized by IR and NMR ( 1 H and 13 C) spectroscopy (RSH = 2-aminoethanethiol hydrochloride (Aet), cysteine (Cys), thiosalicylic acid (Ts) and 2-mercaptonicotinic acid (Mnt)). The spectral data suggests that the coordination of thiolates to mercury(II) occurs through the sulfur as indicated by the absence of S-H vibrations in IR and significant downfield shifts in the C-S resonance in 13 C NMR. However, in Mnt complexes, coordination through both sulfur and nitrogen is indicated. Antimicrobial activities of the complexes were evaluated by minimum inhibitory concentration and the results showed that the complexes exhibited a wide range of activities against gram-negative bacteria (E. coli, P. aeruginosa), while moderate activity was observed against a mold, P. citrinum.

Alkali-Metal-Directed Hydrolytic Condensation of 3-Mercaptopropyltrimethoxysilane

“…The latter one can be assigned as a resonance of the CH 2 group bonded to a SK moiety. A similar down-field shift of appropriate 13 C resonances with respect to free ligands was observed for Hg (II) thiolates [40]. The spectra of sodium cyclosiloxanolate (Table 1/ (Figure SI 4).…”

Synthesis, structural and mass spectrometric investigations of pyridinium bis(thiosalicylato)mercurate(II)

“…[5] A more recent preparation omitted the use of a base. [6] [Hg(SC6H4-2-CO2H)2] has been structurally characterised as its 1,4-dioxane solvate and shown to contain a linear two-coordinated mercury(II) centre; 1,4-dioxane molecules link the mercury…”

Surface Layer‐by‐Layer Chemical Deposition Reaction for Nanosized Thin‐Film Formation of Metal Complexes of 2‐Mercaptonicotinic Acid

“…The antimicrobial activity of mercury(II) complexes of 2-mercaptonicotinic acid derivatives were evaluated. [29] Pd II and Pt II complexes of 2-mercaptonicotinic acid with the formula [M(mercaptonicotinic acid)Cl] were also synthesized and characterized. [30] The interaction of polyfunctional 2-mercaptonicotinic acid with the ruthenium(III)-EDTA complex [31] and the synthesis, crystal structures, and coordination modes of Pd II , Pt II , Re III , and Mo VI complexes of 2-mercaptonicotinic acid were also studied.…”