Synthesis, spectroscopic and structural characterization, and antimicrobial studies of metal complexes of a new hexadentate Schiff base ligand. Spectrophotometric determination of Fe(III) in water samples using a recovery test

Zayed, Ehab M.; Ismail, Eman Abdel Rahman; Khalil, Mostafa M.H.; Kamel, Amany Hany Mohamed

doi:10.1007/s00706-013-1131-3

Cited by 40 publications

(11 citation statements)

References 27 publications

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“…This value corresponds to one unpaired electron and thus offers evidence for mononuclear structure of the complex. For all four complexes, Table 6 shows their magnetic moment values, which support the suggestion of octahedral structure [43].…”

Section: Magnetic Momentsupporting

confidence: 77%

Thermal studies and mass loss inhibition for some new mixed amino acid metal complexes with their applications

Isamil

Al-blewi

Soliman

et al. 2016

J Therm Anal Calorim

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A thermal gravimetric analysis was studied for the new metal mixed-ligand complexes of copper(II), nickel(II), cobalt(II), and zinc(II) metals formed with glutamic acid as a primary ligand and nitrilotriacetic acid (H 3 NTA) as a secondary ligand which have been characterized by their elemental analysis, magneto-chemical measurements, Fourier transform infrared (FTIR), UV-Vis spectrophotometer, thermal gravimetric analysis, and mass spectroscopy studies. Glutamic acid in these complexes acts as a bidentate ligand, coordinating through the one nitrogen of the amino group and one oxygen of the carboxylate group, whereas nitrilotriacetic acid shows a tridentate nature, and the coordination occurs through two carboxylate oxygen and one nitrogen of the amino group. Water molecules satisfy the remaining coordination positions. The complexes have been suggested to show geometry of an octahedral symmetry. The results were indicated that the mixed complexes were isolated in 1:1:1 molar ratio (metal-glutamic-HNTA), and the molecular structures were suggested to be [M(glutamic)(HNTA) (H 2 O)]Á(2-1.5)H 2 O. The antimicrobial activities of our prepared complexes evaluated against Escherichia coli, Staphylococcus aureus, Candida albicans, and Aspergillus flavus (isolates from Micro-analytical Center, Faculty of Science, Cairo University) were investigated. Also, our prepared complexes were evaluated for their in vitro anticancer activity against hepatocellular carcinoma. In addition, the mass loss inhibition effects for copper and aluminum metal plates by our prepared complexes in 1 M HCl were studied.

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Section: Magnetic Momentsupporting

confidence: 77%

Thermal studies and mass loss inhibition for some new mixed amino acid metal complexes with their applications

Isamil

Al-blewi

Soliman

et al. 2016

J Therm Anal Calorim

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“…The observed magnetic moment of the Fe(III) complex is 5.35 B.M. Thus, the complex formed has octahedral geometry involving d 2 sp 3 hybridization in Fe(III) ion [33]. The spectrum also shows a band at 24 805 cm −1 which may attribute to ligand to metal charge transfer.…”

Section: Magnetic Susceptibility and Reflectance Spectral Studiesmentioning

confidence: 86%

Synthesis, DFT calculation, DNA-binding, antimicrobial, cytotoxic and molecular docking studies on new complexes VO(II), Fe(III), Co(II), Ni(II) and Cu(II) of pyridine Schiff base ligand

Alzamil

2020

Mater. Res. Express

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A new H 2 L ligand (6, 6′-(pyridine-2, 6-diylbis(azan-1-yl-1-ylidene))bis(methan-1-yl-1-ylidene)bis(2ethoxyphenol) was obtained from the reaction of 2, 6-diamino pyridine and 3-ethoxy salicyaldehyde in 1:2 molar ratio and fully characterized using elemental analyses and spectroscopic tools. The reaction of a ligand with the different metal salts yields five new complexes CuL, CoL, NiL, FeL, and VOL. The new complexes were identified according to the results of elemental analyses, IR and UV-vis spectra, magnetic moment, molar conductance and thermal analyses (TGA). From the conductivity data, it is deduced that all complexes are non-electrolytes. FT-IR spectra displayed that the Schiff base ligand coordinated to the metal ions in a manner with ONNO donor sites, the nitrogen atom of the pyridine ring, the nitrogen of one azomethine group and two oxygen atoms of the two phenolic OH groups. The results of electronic spectra and magnetic susceptibility confirmed octahedral geometry of FeL complex and square pyramidal geometry for CoL, CuL and VOL and square planar for NiL. The electronic structure of H 2 L ligand and its complexes were investigated theoretically at the DFT-B3LYP-311 G ** level of the theory. FT-IR spectra established the involvement of pyridine nitrogen in the coordination process. The presence of coordinated water molecules inside the coordination sphere of the complexes CoL, CuL and FeL are supported by TGA studies. The antimicrobial activities of the ligand and its complexes were determined against two Gram-positive bacteria (B. subtitles and S. aureus) and two Gram-negative (E. coli and P. vulgaris) and two fungus (Candida albicans and Aspergilla's fumigates). The results showed that the complexes behaved as better antimicrobial agents than the ligand, VOL complex shows exceptional antimicrobial efficacy. The order of increasing the antibacterial and antifungal potency is H 2 L<NiL<CuL<CoL< FeL<VOL. The binding of the complexes with CT-DNA was followed using electronic absorption, viscosity and gel-electrophoresis measurements. These studies confirmed that the complexes bind to CT-DNA through a groove binding mode with certain affinities (Kb=6.25×10 5 , 5.50×10 5 , 3.20×10 5 , 2.50×10 5 and 1.52×10 5 for CuL, FeL, VOL, NiL, and CoL respectively). Moreover, cytotoxic effect against hepatocellular carcinoma cell line (HEP-G2) was screened. The IC 50 values of the ligand and complexes suggest that the compounds possess very good cytotoxic activity and follow the order: CuL > FeL > VOL > NiL > CoL>H 2 L. These results strongly agree with results of binding constant of CT-DNA with different metal complexes.

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“…e synthesized nano cobalt oxide is confirmed by the EDX spectrum measurement shown in Figure 9, which confirms the highest formation percent of cobaltosic oxide Co 3 is investigation was performed using the diffusion agar technique ( Figure 5S). e assays collection included [30,45]. e inhibitory effects of the used ligands and their ternary polymer complexes against the used organisms are given in Table 6.…”

Section: Edx Of Nano Cobaltosic Oxidementioning

confidence: 99%

“…Cell viability was assessed by the mitochondrial-dependent reduction of yellow MTT (3-(4,5-dimethylthiazol-2-yl)-2,5- diphenyl tetrazolium bromide) to insoluble purple formazan [45]. e prepared ternary metal complexes are of different viability percentages as depicted in Figure 10.…”

Section: Cytotoxicitymentioning

confidence: 99%

Transition Metal Complexes of Mixed Bioligands: Synthesis, Characterization, DFT Modeling, and Applications

Abdel‐Mottaleb

Ismail

2019

Journal of Chemistry

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Divalent transition metal complexes [MGlu-Arg (H2O)]H2O and [MGlu-Arg (H2O)]H2O, where M = Co, Ni, Cu, and Zn, Glu = glutamic acid, and Arg = L-arginine, are prepared and characterized using different techniques. DFT and TD-DFT modelling validated and interpreted some experimental results. Weight loss technique reveals efficient corrosion inhibition action of these complexes towards aluminum metal at different temperatures. Our results point to corrosion inhibition through chemical adsorption on the aluminum surface. Additionally, a facile calcination of Co and Cu complexes at 550°C yields nanosized oxides of Co3O4, CoO, and CuO crystalline phases. The complexes show remarkable biological activities towards pathogenic bacteria and fungi. Moreover, in vitro anticancer activity evaluation of these complexes is achieved against hepatocellular carcinoma (HepG-2). The results are correlated with molecular descriptors such as chemical potential and hardness obtained from the frontier orbitals.

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Synthesis, spectroscopic and structural characterization, and antimicrobial studies of metal complexes of a new hexadentate Schiff base ligand. Spectrophotometric determination of Fe(III) in water samples using a recovery test

Cited by 40 publications

References 27 publications

Thermal studies and mass loss inhibition for some new mixed amino acid metal complexes with their applications

Thermal studies and mass loss inhibition for some new mixed amino acid metal complexes with their applications

Synthesis, DFT calculation, DNA-binding, antimicrobial, cytotoxic and molecular docking studies on new complexes VO(II), Fe(III), Co(II), Ni(II) and Cu(II) of pyridine Schiff base ligand

Transition Metal Complexes of Mixed Bioligands: Synthesis, Characterization, DFT Modeling, and Applications

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