Synthesis, spectroscopic and DNA interaction studies on bis(1-amidino-O-2-alkoxyethylurea)Cu(II)nitrate where alkoxy=methoxy, ethoxy or butoxy

Devi, N. Shantibala; Singh, L. Jaideva; Devi, S. Pramodini; Singh, Raj K.; Singh, Ritu; Rajeswari, B.; Kadam, R.M.

doi:10.1016/j.molstruc.2014.08.005

Cited by 8 publications

(5 citation statements)

References 51 publications

(44 reference statements)

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“…The CT bands of complex 3 (500 μM) in Trisbuffer solution at 257 nm ( Fig. 5 (e) The spectral patterns of complexes 1 to 4 were analogous to previously reported complexes whose interaction mode with DNA is nonintercalative and groove binding [30][31][32][33]. The intrinsic binding constant, K b for each complex was determined from the plot of [DNA] / (ε a -ε f ) versus [DNA], (Fig.…”

Section: Electronic Absorption Titrationsupporting

confidence: 67%

“…The K b values suggest weaker DNA binding affinity of the complexes than the classical intercalators [49][50][51][52][53]. From the observed results and finding the binding modes of the complexes were non-intercalative and groove or surface binding [30][31][32][33].…”

Section: Electronic Absorption Titrationmentioning

confidence: 99%

“…The interaction of transition metal complexes with DNA continues to attract interest in relation to enzyme-DNA interaction and in the search for anticancer chemotherapeutic agents [29][30][31][32][33][34][35][36][37]. Transition metal complexes can bind to DNA via covalent and/or non-covalent interactions [29].…”

Section: Introductionmentioning

confidence: 99%

“…The labile ligand of metal complex such as chloride can be replaced by base nitrogen of DNA to form covalent bonds [29]. The noncovalent DNA interactions include (1) electrostatic interaction with the phosphates, (2) intercalative insertion between base pairs, and (3) groove binding [32][33][34][35][36][37].…”

Section: Introductionmentioning

confidence: 99%

“…In view of above importance and in continuation of our research in the field of biologically active complexes [30][31][32][33], we herein report the syntheses, spectroscopic characterization and DNA binding studies of Mn(II), Co(II), Ni(II) and…”

Section: Introductionmentioning

confidence: 99%

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Synthesis, Characterization and DNA Binding Studies of (E)-1-((Pyridin-2-yl)methylidene) semicarbazide Mn(II), Co(II), Ni(II) and Cu(II) Complexes

U-wang

Singh

Devi

et al. 2019

CSIJ

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(E)-1-((pyridin-2-yl)methylidene)semicarbazide (PMSC) complexes of [Mn(PMSC)2 ]Cl2 (1), [Co(PMSC)2]Cl2 (2), [Ni(PMSC)2]Cl2.5H2O (3), and [Cu(PMSC)(H2O)]Cl2 (4) have been synthesized and characterized by different spectroscopic techniques, EPR, magnetic susceptibility and thermal stability measurements. Complex 3 crystallizes as octahedral coordination complex in monoclinic crystal system. Complexes 1 and 2 have been found to have octahedral geometries and 4 to have square planar geometry. The complexes were found to be groove binding to calf-thymus DNA.

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Section: Electronic Absorption Titrationsupporting

confidence: 67%

Section: Electronic Absorption Titrationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Synthesis, Characterization and DNA Binding Studies of (E)-1-((Pyridin-2-yl)methylidene) semicarbazide Mn(II), Co(II), Ni(II) and Cu(II) Complexes

U-wang

Singh

Devi

et al. 2019

CSIJ

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Synthesis, crystal structures, DNA binding, and cytotoxicity activities of two copper(II) complexes based on unsymmetrical tripodal ligands

Zhang

Zhao

et al. 2015

Journal of Coordination Chemistry

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Synthesis, crystal structure, redox behavior and DNA-binding properties of a series of copper(II) complexes with two new carboxamide derivatives

Mondal

Sen

Maji

et al. 2015

Journal of Coordination Chemistry

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Four mononuclear copper(II) complexes of two new carboxamide derivatives formulated as [Cu(L1)2](ClO4)2 (1a), [Cu(L1)2](NO3)2 (1b), [Cu(L2)2(H2O)2](ClO4)2 (2a), and [Cu(L2)2(H2O)](NO3)2(2b) have been isolated in pure form from the reaction of L1 and L2 [where L1 = N-(furan-2-ylmethyl)-2-pyridinecarboxamide and L2 = N-(thiophen-2-ylmethyl)-2-pyridinecarboxamide] with copper(II) salts of perchlorate and nitrate. All the complexes were characterized by physicochemical and spectroscopic tools along with single-crystal X-ray diffraction studies. The structural analyses\ud showed that 1 is monomeric of square planar geometry with copper(II) chelated by two L1 ligands. Complex 2 differs in coordination geometry, being octahedral and distorted square pyramidal. Two L2 ligands occupy the equatorial positions of the octahedral 2a and the basal sites of the pyramidal\ud 2b, with water molecules that complete the coordination sphere in each case. Electrochemical studies using cyclic voltammetry showed a reversible redox behavior of the copper(II) in 1 and 2. The electronic spectroscopic behavior and the trend of one electron equivalent redox potential corresponding to a CuII/CuI couple have also been confirmed by density functional theory calculations. The spectroscopic and viscosity measurement study in tris–HCl buffer suggested an intercalative interaction of 1a and 2 with calf thymus DNA likely due to the stacking between the non-coordinated\ud furan and thiophene chromophore with the base pairs of DNA

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Synthesis, spectroscopic and DNA interaction studies on bis(1-amidino-O-2-alkoxyethylurea)Cu(II)nitrate where alkoxy=methoxy, ethoxy or butoxy

Cited by 8 publications

References 51 publications

Synthesis, Characterization and DNA Binding Studies of (E)-1-((Pyridin-2-yl)methylidene) semicarbazide Mn(II), Co(II), Ni(II) and Cu(II) Complexes

Synthesis, Characterization and DNA Binding Studies of (E)-1-((Pyridin-2-yl)methylidene) semicarbazide Mn(II), Co(II), Ni(II) and Cu(II) Complexes

Synthesis, crystal structures, DNA binding, and cytotoxicity activities of two copper(II) complexes based on unsymmetrical tripodal ligands

Synthesis, crystal structure, redox behavior and DNA-binding properties of a series of copper(II) complexes with two new carboxamide derivatives

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