Synthesis, spectral studies and structure of 2-hydroxyacetophenone nicotinic acid hydrazone

Synthesis, spectroscopic characterization and crystal structure of mixed ligand Ni(II) complex of N-4-diethylaminosalicylidine-N′-4-nitrobenzoyl hydrazone and 4-picoline

“…The coordination properties of heterocyclic hydrazones have extensively been investigated [1][2][3][4][5][6]. They constitute an important class of biologically active molecules, which have attracted attention due to their wide-ranging pharmacological applications such as antitubercular agents and iron chelators [7][8][9][10].…”

Comparative ligational, optical band gap and biological studies on Cr(III) and Fe(III) complexes of hydrazones derived from 2-hydrazinyl-2-oxo-N-phenylacetamide with both vanillin and O-vanillin

“…The multiplicity of donor sites make them more flexible that can form different modes of chelation with transition metal ions and then several applications can be carried out. Hydrazones are used in analytical chemistry as selective metal extracting agents as well as in spectroscopic determination of certain transition metal ions [1]. Hydrazone derivatives are found to possess antimicrobial [2,3], anti-tubercular [4], anti-convulsant [5] and anti-inflammatory activities [6][7][8].…”

“…The electronic spectra of the complexes were recorded from 200 to 900 nm in DMSO solution on a Perkin Elmer Lamda 25 UV/Vis Spectrophotometer. 1 H-NMR measurements in d 6 -DMSO at room temperature were carried out on Mercury and Gemini 300 MHZ spectrometer.…”

6-Hydrazinonicotinic acid hydrazide: an useful precursor for chemo- and regioselective synthesis of new heteroaryl-linked pyridinohydrazones

“…[3][4][5][6] Hydrazones are also important compounds for drug design, as possible ligands for metal complexes, organocatalysis, and also for the syntheses of heterocyclic compounds. 7,8 The ease of preparation, increased hydrolytic stability relative to imines, and tendency toward crystallinity are all desirable characteristics of hydrazones. Due to these positive traits, hydrazones have been under study for a long time, but much of their basic chemistry remains unexplored.…”