Synthesis, spectral characterization and antimicrobial activity of some M(II) complexes with Ciprofloxacin

Horozić, Emir; Cipurković, Amira; Ademović, Zahida; Bjelošević, Demir; Zukić, Amila; Kolarević, Lamija; Husejnagić, Darja; Hodzic, Snjezana

doi:10.7251/jepm181002016h

Cited by 5 publications

(4 citation statements)

References 25 publications

(28 reference statements)

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“…2,2-diphenyl-1-picryl-hydrazyl (DPPH) method was performed according to earlier described method [37]. 100 μL of extract was mixed with 1900 μL of methanol and 500 μL of 0.5 mM DPPH radical solution.…”

Section: Dpph Radical Scavenging Activitymentioning

confidence: 99%

Influence of Deep Eutectic Solvents (DESs) on Antioxidant and Antimicrobial Activity of Seed Extracts of Selected Citrus Species

Kolarević

Horozić

Ademović

et al. 2020

IRJPAC

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Deep eutectic solvents (DESs), as an alternative to ionic liquids, have greener credentials than ionic liquids and have attracted increasing attention in many applications. Choline chloride-based DESs in combination with different hydrogen bond donors (organic acid, sugars and urea), showed a high extraction efficiency. The aim of this study was to examine the possible effects of choline chloride-based eutectic solvents on the antioxidant and antimicrobial activity of lemon and mandarin orange seed extracts. Lactic acid, glucose, urea and water were used to prepare choline chloride-based Natural Deep Eutectic Solvents (NADESs). Ferric-Reducing Antioxidant Power (FRAP) Assay and 2,2-diphenyl-1-picryl-hydrazyl (DPPH) method were used to determine antioxidant activity. Antibacterial activity was investigated by diffusion method on reference bacterial strains E. coli, E. faecalis, S. aureus, B. subtilis and L. monocytogenes. The analysis revealed a significant reduction potential of the eutectic solvent based on lactic acid as well as significant antioxidant activity of lemon and mandarin seed extracts. In general, mandarin extracts showed better antioxidant capacity. In vitro antibacterial activity assays showed a complete absence of bacterial growth inhibition of the extracts. However, eutectic solvents with lactic acid have shown a significant antimicrobial effect.

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Section: Dpph Radical Scavenging Activitymentioning

confidence: 99%

Influence of Deep Eutectic Solvents (DESs) on Antioxidant and Antimicrobial Activity of Seed Extracts of Selected Citrus Species

Kolarević

Horozić

Ademović

et al. 2020

IRJPAC

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“…[13] A large number of metal complexes synthesized so far with various oxygen, nitrogen, sulfur or combined ligands have shown antitumor, antibacterial, antifungal, antituberculous and antihypertensive effects. [14][15][16][17] In addition, complexes are now being studied as potential synthetic antioxidants and yielding promising results in in vitro and in vivo studies.…”

Section: Metal Complexesmentioning

confidence: 99%

Metal complexes as potential agents for neutralizing free radicals: a review of in vitro studies

Imamovic¹,

Horozić²,

Salkovic³

et al. 2023

Acta Med Sal

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Metal complexes due to their antibacterial, antifungal, antitumor and antioxidant properties have been extremely studied today. A large number of metal complexes have the ability to neutralize free radicals, which most often occur as a result of metabolic processes in the body, smoking, exposure to radiation and chemical substances. Testing the antioxidant capacity of metal complexes can be tested by various methods in vitro and in vivo. This paper will present the efficiency of neutralization of free radicals by metal complexes synthesized in the past few years using different ligands, as well as the most commonly used methods for testing the antioxidant capacity of this group of compounds.Â

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“…2,2-diphenyl-1-picryl-hydrazyl (DPPH) method was performed according to earlier described method [10]. Two concentrations of the extract, 0.5 and 1 mg/mL, were used to test the inhibition of the extract.…”

Section: Determination Of Antioxidant Capacitymentioning

confidence: 99%

Influence of Solvents and Solvent Mixtures on the Content of Polyphenols and Antioxidant Activity of Capsella bursa-pastoris (L.) Medik. Extracts

Horozić,

Huseinović,

Mekić

et al. 2023

JSRR

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Capsella bursa-pastoris (L.) Medik. (known as shepherd's purse) is a plant whose parts are used as medicine in herbal medicine. It is applicable as a medicine in the treatment of all forms of internal bleeding, for the treatment of hemorrhoids, excessive menstruation, but also for the usual stopping of nosebleeds. Through this research, the influence of organic solvents and their aqueous mixtures on the efficiency of polyphenol extraction and antioxidant activity was compared. The inhibition of free radicals was tested by the DPPH method, while the FRAP method was used to test the reduction potential. Analyzes have shown that water is the most effective solvent in the isolation of polyphenols from the aerial parts of shepherd's purse. Mixtures of organic solvents with water also showed high efficiency in the extraction of bioactive components, while the weakest results were obtained for extracts prepared in pure organic solvents.

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Synthesis, spectral characterization and antimicrobial activity of some M(II) complexes with Ciprofloxacin

Cited by 5 publications

References 25 publications

Influence of Deep Eutectic Solvents (DESs) on Antioxidant and Antimicrobial Activity of Seed Extracts of Selected Citrus Species

Influence of Deep Eutectic Solvents (DESs) on Antioxidant and Antimicrobial Activity of Seed Extracts of Selected Citrus Species

Metal complexes as potential agents for neutralizing free radicals: a review of in vitro studies

Influence of Solvents and Solvent Mixtures on the Content of Polyphenols and Antioxidant Activity of Capsella bursa-pastoris (L.) Medik. Extracts

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