Synthesis, spectral and biological studies of organotin(IV) complexes of heteroscorpionate

Abstract

A heteroscorpionate ligand, potassium hydrobis(benzoato)(salicylaldehyde)borate (KL), has been synthesized. This was converted into organotin complexes R 2 SnL 2 and R 3 SnL complexes by mixing and stirring with a methanolic solution/suspension of organotin chloride. The ligand and its complexes were characterized by elemental analyses and spectral studies (IR, 1 H NMR, 13 C NMR, ESI mass spectra and Thermo gravimetric analysis (TGA)). Antibacterial and antifungal studies of these compounds were evaluated by the disc diffusion method at variable concentration against three species of bacteria (Staphylococcus aureus, Klebsiella pneumonia and Bacillius subtillis) and two species of fungi (Asperjillius fiavus and Candida albicans). It was found that triorganotin derivatives (R 3 SnL) of the ligand were more effective as compared with diorganotin derivatives (R 2 SnL 2 ). The organotin complexes of borates were tested for their algicidal activity on the cyanobacterial strains Aulosira fertilissma, Anabaena species, Anabaena variabilis and Nostoc muscorum and showed high to moderate toxicity towards the above species. The ligand and its complexes were also tested for its pH effect on soil in vitro for a duration of more than one month and it was found that they are able to kill pests without damaging the soil quality.

A Quantitative Assay of Sodium Triacetoxyborohydride

“…This difference in reactivity may result from mixed borohydride 7 as an active intermediate in the case of 1 that facilitates the reduction (eq ). Support for this proposal was secured when 1 H NMR experiments revealed phenol/acetic acid exchange when STAB and phenol were present in solution and when a new signal was detected in the 11 B NMR spectrum upon addition of phenol to STAB . Furthermore, a 1 H NMR spectrum acquired when STAB was added to a solution of 5 in CD 3 CN showed splitting of the aromatic and aldehydic peaks as well as free AcOH, suggestive of a borate analogous to 7 . …”

Synthesis, Characterization and DFT Study of Bioactive 2‐[(2‐Methylpropanoyl)amino]propanoic Acid and Its Polymeric Tributyltin(IV) Derivative

“…Organotin(IV) complexes have diverse structural motifs depending on the number and nature of ligands and show numerous biological properties including insecticidal, anti‐tuberculosis, anti‐proliferative, anti‐diabetic, anti‐fungal and anti‐bacterial . In case of macrocyclic organotin(IV) complexes, fluorescent and good anti‐tumor properties are also observed.…”

Synthesis, Characterization and Antimicrobial Activity of Potassium Hydro(benzoyl)(phthalyl)borate and Its Cobalt(II), Nickel(II), and Copper(II) Complexes

“…14,15 Use of metal complexes as diagnostic agents is a relatively new area of medicinal research and has flourished rapidly for the last 4-5 decades. During recent years complexation of biologically active ligands 16,17 has received much attention.…”