Synthesis, physico-chemical studies of manganese(II), cobalt(II), nickel(II), copper(II) and zinc(II) complexes with some <i>p</i>-substituted acetophenone benzoylhydrazones and their antimicrobial activity

Singh, Vinod P.; Singh, Shweta; Katiyar, Anshu

doi:10.1080/14756360802318662

Cited by 20 publications

(2 citation statements)

References 32 publications

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“…Fungal and bacterial infections are yet posing serious challenges to the human beings throughout the world [15][16][17][18][19][20][21][22][23] . Newly emerging resistance to the currently available drugs on the market is the drastic facet of this dilemma.…”

Section: Discussionmentioning

confidence: 99%

Antimicrobial activities of Conyzolide and Conyzoflavone from Conyza canadensis

Shakirullah

Ahmad

Shah

et al. 2010

Journal of Enzyme Inhibition and Medicinal Chemistry

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Antibacterial and antifungal activities of the two isolated compounds from Conyza canadensis have been reported in the current study. The two isolated compounds i.e. Conyzolide (1) and Conyzoflavone (2) were tested against six bacterial and five fungal strains, employing hole diffusion and macrodilution methods. Both the compounds showed significant activities against the tested pathogens with special reference to E. coli, P. aeruginosa, S. aureus, Trichophytom longifusus, C. albicans, and C. glaberata. Conyzolide revealed comparatively better antibacterial activity against E. coli (minimum inhibitory concentration (MIC): 25 µg/mL) in comparison to Conyzoflavone. However, in case of antifungal activities, Conyzoflavone exhibited superior antifungal activity against C. albicans (MIC: 10 µg/mL) as compared to Conyzolide.

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Section: Discussionmentioning

confidence: 99%

Antimicrobial activities of Conyzolide and Conyzoflavone from Conyza canadensis

Shakirullah

Ahmad

Shah

et al. 2010

Journal of Enzyme Inhibition and Medicinal Chemistry

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“…A recent study has linked the antibacterial activity of twenty acetophenones with their structural characteristics by electronic and topological indices [4]. Balan and co-workers have reported that diazinium salts with dihydroxyacetophenone skeleton exhibit antimicrobial activity [5] and the complexes between p-substituted acetophenone and benzoylhydrazones present antifungal activity [6], [7]. Different flavonoids such as chalcones, flavones and flavanones are obtained by reaction between acetophenones and benzaldehydes, in alkaline medium [8], [9].…”

Section: Introductionmentioning

confidence: 99%

Intermolecular interactions, spectroscopic and theoretical investigation of 4-aminoacetophenone

Rocha,

Di Santo,

Ben Altabef

et al. 2019

IJAC

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The molecular structure of 4-aminoacetophenone (PAAP) was determined by DFT calculations using different basis sets. The structural parameters, electronic properties and vibrational wavenumbrers of the optimized geometry have been determined. The vibrational wave-numbers of the fundamental modes of the title compound have been precisely assigned and analyzed and the theoretical results are compared with the experimental vibrations observing a very good correlation. TD-DFT approach was applied to assign the electronic transitions ob-served in the experimental UV-vis spectrum. The molecular electrostatic potential map was used to identify the possible electrophilic and nucleophilic sites. Natural bond orbital (NBO) analysis and atoms in molecules (AIM) approach are applied in order to quantify the relative strength of hydrogen bonding interactions and to account their effect on the stabilities of molecular arrangements. In addition, a detailed exploration of the intermolecular interactions that stabilizes the crystal packing has been performed by using the Hirshfeld surface analysis.Â Â Â

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Acid–Base and Solvation Properties of Metal Enolates Part 2: Transition‐Metal Enolates and Medium Effects

Bastos

2017

Patai's Chemistry of Functional Groups

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Synthesis, physico-chemical studies of manganese(II), cobalt(II), nickel(II), copper(II) and zinc(II) complexes with some p-substituted acetophenone benzoylhydrazones and their antimicrobial activity

Cited by 20 publications

References 32 publications

Antimicrobial activities of Conyzolide and Conyzoflavone from Conyza canadensis

Antimicrobial activities of Conyzolide and Conyzoflavone from Conyza canadensis

Intermolecular interactions, spectroscopic and theoretical investigation of 4-aminoacetophenone

Acid–Base and Solvation Properties of Metal Enolates Part 2: Transition‐Metal Enolates and Medium Effects

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